, Question 1:
Which medication class is most appropriate for treating a patient
with chronic heart failure and reduced ejection fraction?
a) Calcium channel blockers
b) Beta-blockers
c) Thiazide diuretics
d) ACE inhibitors
Correct Answer: d) ACE inhibitors
Rationale: ACE inhibitors improve symptoms and survival in
patients with chronic heart failure by reducing afterload and
preload, thereby enhancing cardiac output.
Question 2:
For a patient with Type 2 diabetes and a history of cardiovascular
disease, which medication would provide cardiovascular benefits
beyond blood glucose control?
,b) Sulfonylureas
c) GLP-1 receptor agonists
d) DPP-4 inhibitors
Correct Answer: c) GLP-1 receptor agonists
Rationale: GLP-1 receptor agonists have been shown to reduce
major cardiovascular events in patients with Type 2 diabetes and
cardiovascular disease.
Question 3:
Which of the following is a core pharmacokinetic parameter to
consider for a drug with a narrow therapeutic index?
a) Efficacy
b) Clearance
c) Palatability
d) Erythrocyte binding
Correct Answer: b) Clearance
Rationale: For drugs with narrow therapeutic indices, monitoring
clearance is crucial to avoid toxicity or subtherapeutic dosing.
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