Virology Final Exam Questions with Correct
Answers
All RNA viruses EXCEPT RETROVIRUSES encode what kind of
polymerase? (1 pt)
a) RNA polymerase II
b) DNA polymerase
c) RNA dependent RNA polymerase
d) Reverse transcriptase Correct Answer-c
The key molecule in the replication of all viruses is (1 pt)
a) RNA
b) DNA
c) mRNA
d) None of the above Correct Answer-c
Type I interferon molecules block virus replication by (2 pts)
a) Blocking virus entry
b) Activating RNase L to degrade mRNA
c) Activating dsRNA dependent protein kinase to inhibit protein
translation
d) Inhibiting virus assembly Correct Answer-b c
Which of the following virus contains a dsRNA genome (1 pt)
,a) HIV-1
b) Influenza virus A
c) SARS virus
d) Reovirus Correct Answer-d
Which of the following virus contain an ambisense RNA genome (1 pt)
a) Herpes simplex virus-1
b) Pox virus
c) Rabies virus
d) Hantavirus Correct Answer-d
Which of the following virus contain a segmented genome (1 pt)
a) HIV-1
b) Rotavirus
c) Influenza virus
d) Coronavirus Correct Answer-d
Circle the emerging viruses that are associated with bats (3 pts)
a) SARS virus
b) Hendra virus
c) Ebola virus
d) Hantavirus Correct Answer-a b c
,Which of the following toll-like receptor recognizes primarily dsRNA
and viruses? (1 pt)
a) TLR2
b) TLR3
c) TLR4
d) TLR9 Correct Answer-b
Most (-) RNA viruses have (2 pts)
a) Icosahedral capsids
b) Helical capsids
c) Envelopes
d) None of the above Correct Answer-b c
Which of the following characteristics differentiates latent infection
from chronic infection
(1 pt)
a) No virus replication
b) No mRNA transcription
c) None of the above
d) Both a and b Correct Answer-a
Which of the following proteins are not oncogenes? (1 pt)
a) Src
b) Myc
, c) Sis
d) T (tumor) antigen of simian virus 40 Correct Answer-d
Which of the following immune cells belong to the professional antigen-
presenting cells? (2 pts)
a) Macrophages
b) Neutrophils
c) Natural killer
d) Dendritic cells Correct Answer-a d
Which of the following cytokines are important in promoting Th2
response? (1 pt)
a) IL-4
b) IL-1
c) IL-12
d) Tumor necrosis factor alpha Correct Answer-a
Which of the following are important determinants of the tissue tropism
of viruses? (2 pts)
a) Viral glycoproteins
b) Cellular proteins and enzymes
c) Viral RNA dependent RNA polymerase
d) Cellular RNA polymerase II Correct Answer-b
Answers
All RNA viruses EXCEPT RETROVIRUSES encode what kind of
polymerase? (1 pt)
a) RNA polymerase II
b) DNA polymerase
c) RNA dependent RNA polymerase
d) Reverse transcriptase Correct Answer-c
The key molecule in the replication of all viruses is (1 pt)
a) RNA
b) DNA
c) mRNA
d) None of the above Correct Answer-c
Type I interferon molecules block virus replication by (2 pts)
a) Blocking virus entry
b) Activating RNase L to degrade mRNA
c) Activating dsRNA dependent protein kinase to inhibit protein
translation
d) Inhibiting virus assembly Correct Answer-b c
Which of the following virus contains a dsRNA genome (1 pt)
,a) HIV-1
b) Influenza virus A
c) SARS virus
d) Reovirus Correct Answer-d
Which of the following virus contain an ambisense RNA genome (1 pt)
a) Herpes simplex virus-1
b) Pox virus
c) Rabies virus
d) Hantavirus Correct Answer-d
Which of the following virus contain a segmented genome (1 pt)
a) HIV-1
b) Rotavirus
c) Influenza virus
d) Coronavirus Correct Answer-d
Circle the emerging viruses that are associated with bats (3 pts)
a) SARS virus
b) Hendra virus
c) Ebola virus
d) Hantavirus Correct Answer-a b c
,Which of the following toll-like receptor recognizes primarily dsRNA
and viruses? (1 pt)
a) TLR2
b) TLR3
c) TLR4
d) TLR9 Correct Answer-b
Most (-) RNA viruses have (2 pts)
a) Icosahedral capsids
b) Helical capsids
c) Envelopes
d) None of the above Correct Answer-b c
Which of the following characteristics differentiates latent infection
from chronic infection
(1 pt)
a) No virus replication
b) No mRNA transcription
c) None of the above
d) Both a and b Correct Answer-a
Which of the following proteins are not oncogenes? (1 pt)
a) Src
b) Myc
, c) Sis
d) T (tumor) antigen of simian virus 40 Correct Answer-d
Which of the following immune cells belong to the professional antigen-
presenting cells? (2 pts)
a) Macrophages
b) Neutrophils
c) Natural killer
d) Dendritic cells Correct Answer-a d
Which of the following cytokines are important in promoting Th2
response? (1 pt)
a) IL-4
b) IL-1
c) IL-12
d) Tumor necrosis factor alpha Correct Answer-a
Which of the following are important determinants of the tissue tropism
of viruses? (2 pts)
a) Viral glycoproteins
b) Cellular proteins and enzymes
c) Viral RNA dependent RNA polymerase
d) Cellular RNA polymerase II Correct Answer-b
