Virology Exam #2 Review Questions with Correct Answers
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Course
Virology
Institution
Virology
- Do all viruses need a primer for their genome replication? Correct Answer-o No, some viruses are able to be self-prime with their own genome. Others use RNA primers and some use protein primers.
- Describe how viruses in class VI and VII replicate their genomes. Correct Answer-o Class VI: (+) ...
Virology Exam #2 Review Questions with Correct
Answers
- Do all viruses need a primer for their genome replication? Correct
Answer-o No, some viruses are able to be self-prime with their own
genome. Others use RNA primers and some use protein primers.
- Describe how viruses in class VI and VII replicate their genomes.
Correct Answer-o Class VI: (+) ssRNA to (-) ssDNA to dsDNA to (+)
ssRNA using viral RNA-dependent DNA polymerase and host DNA-
dependent RNA polymerase
o Class VII: dsDNA to (+) ssRNA to (-) ssDNA to dsDNA using host
DNA-dependent RNA polymerase and viral RNA-dependent DNA
polymerase
- What is semi-conservative replication? Correct Answer-o Semi-
conservative replication describes replication in which each daughter
strand contains one strand of the parents molecule.
- Do plus-stranded RNA-viruses produce minus-stranded RNAs during
their genome replication? Correct Answer-o Yes they do, they simply
generate more (+) ssRNA.
- Do RNA viruses use host produced RNA-dependent RNA polymerase
for their genome replication? Correct Answer-o No, they must use viral
RNA-dependent RNA polymerase.
, - Can proteins be used as primer for viral genome replication? Correct
Answer-o Yes they can with certain viruses.
- What is a concatemer? Describe how a concatemer is created. Correct
Answer-o A concatemer is a linear group of multiple viral genomes
connected together generated by rolling circle replication.
- Compare and contrast genome replication between class VI and class
VII viruses. Correct Answer-o Similarities: use. Viral RNA-dependent
RNA polymerase and host DNA-dependent RNA polymerase
o Differences: Step One of replication
- Why don't viruses get "stuck" on the cellular receptors as they are
released from the host cell? Correct Answer-o Viruses exit cells through
different ways, such as lysis by breaking peptidoglycan bonds, inhibiting
host enzymes that weaken the cell wall, budding, or extrusion through
the cell surface.
- Do all viruses with simple structures can perform self-assembly in a
test tube? Correct Answer-o No, it requires the correct conditions with
appropriate pH and the presence of certain ions.
- Normally, how do filamentous phages exit from their bacterial hosts?
Correct Answer-o Filamentous (naked) viruses exit via extrusion
through the cell surface, in which ssDNA genomes of phages are coated
with a protein within the cell and then lose this protein as they are
extruded into their capsid.
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