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Virology exam 2 Questions with Correct Answer3
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Virology exam 2 Questions with Correct Answer3
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Virology exam 2 Questions with Correct AnswersDo all viruses need a primer for their genome? Correct Answer-No
- Some viruses need a primer for their genome replication
Describe how viruses in class VI and VII replicated their genomes.
Correct Answer-- Both classes use RNA-dependent DNA polymerase
for their genome replication in cytoplasm.
- Both use host DNA-dependent RNA polymerase II for their genome
replication in nucleus.
- Both requires RNase H to replicate their genome.
- Both need primer for genome replication.
What is semiconservative replication? Correct Answer-a mode of
replication in which after a dsDNA (or dsRNA) genome has been copied
each of the
daughter molecules contains a strand of the original molecule
Do plus-stranded RNA viruses produce minus-stranded RNAs during
their genome replication? Correct Answer-yes
- they are produced at low level compared to the plus-stranded RNAs
Do RNA viruses use host produced RNA-dependent RNA polymerase
for their genome replication? Correct Answer-No
- they only use their own RdRP
, Can proteins be used as primer for viral genome replication? Correct
Answer-yes
What's concatemer ? Describe how concatemer is created. Correct
Answer-Concatemers are long dsRNA molecules made of many copies
of viral genomes. They are produced when circular dsDNA genome is
replicated in rolling circle mode
Compare and contrast genome replication between class VI and class
VII viruses Correct Answer-- Class VI starts their genome replication
with RNA molecule whereas class VII with DNA molecule.
- Class VI use host tRNA as primer whereas class VII use a protein as
primer.
- Class VI integrate their DNA genome into host genome and the
integrated genome will be replicated as part of host genome when cells
divide whereas class VII does not insert their DNA genome into host
genome.
- In class VI, reverse transcriptase and RNase H are different proteins
whereas in class VII a single protein possesses those two enzyme
activities.
WHy don't viruses get stuck on the cellular receptors as they are relates
from the host cell? Correct Answer-- each infected cell produces a very
larger number of new viruses
- the cell receptors will soon become saturated by the new viruses
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