2-hour oral glucose tolerance test; common test for pregnant women ≥ 200 mg/dL
Classic symptoms and random plasma glucose ≥200 mg/dL (classic symptoms:
polyuria, polydipsia, unexplained weight loss)
Basic overview of tx DM - Answer-Step 1: lifestyle and metformin
Step 2: add second job
Step 3: 3 drug combo
Step 4: injectable regimen possibly GLP-1
Biguanides (Metformin) black box and side effects - Answer-Black box: lactic acidosis -
hemodialysis can remove accumulates metformin
Side effects: decreased appetite, nausea, diarrhea, vit b12, folate
Monitor renal function if GFR < 30 dc drug
Sulfonylureas Contraindications - Answer-Pregnancy
Type 1DM
BF
Renal and hepatic dysfunction
Sulfonylureas drug examples and education - Answer--"ides"
Only for type 2 diabetes
Educate on s/s of hypoglycemia
Meglitinides - Answer-Only for type 2 dm, same as sulfonylureas, stimulate pancreatic
insulin release
Contraindicated in liver impairment and gemfibrozil
Meglitinides drugs - Answer-Glinides
TZDs - Answer-Only type 2
Avoid in heart failure and bladder cancer
TZD drugs end in - Answer--"zones"
SGLT2 inhibitors end - Answer--flozin
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