PHCY 631 – SIHD Questions with Correct Answers
acute chronic stable ischemia Correct Answer-SIHD is not an _____
event but rather manifests as either ____ _____ exertional angina or
_____ without clinical symptoms
women metabolic Correct Answer-microvascular angina is more
common in ____ and those with _____ syndrome
vasospasm Correct Answer-coronary _____ represents a form of angina
that results from an increase in coronary vascular tone that can either
occur in normal or diseased vessels
vasospastic Correct Answer-Prinzmetal's angina is a form of _____
angina that does not involve atherosclerotic placque
atherosclerotic LV comorbidities symptoms Correct Answer-prognosis
of pts with SIHD is related to extent of _____ disease, presence of ____
dysfunction, and the presence of other ______. Severity of angina
______ can be useful in determining prognosis.
increase demand decrease supply Correct Answer-the pathophysiology
of SIHD is driven by an (increase/decrease) in myocardial oxygen
______ (supply/demand) in the setting of a fixed (increase/decrease)
myocardial oxygen ______ (supply/demand)
,atherosclerotic plaque Correct Answer-etiology of fixed decrease in
myocardial oxygen supply is long-standing, well-developed ____
______
are not Correct Answer-episodes of angina in SIHD are/are not
associated with ruptured atherosclerotic plaque and thrombus formation
does not Correct Answer-in SIHD, vessel lumen size does/does not
acutely change
HR contractility tension Correct Answer-major determinants of oxygen
demand include ____, myocardial _____, and intramyocardial wall
_____***
size BP muscle mass Correct Answer-intramyocardial wall tension, the
leading contributor to increased MVO2, is directly related to the ____ of
the ventricular cavity and ____ and indirectly to the ventricular ____
_____
physical exertion Correct Answer-rapid increase in ____ ____ is
particularly likely to precipitate angina
HR Correct Answer-generally, events/conditions that cause an increased
_____ can precipitate angina (i.e. fever, exposure to cold, thyrotoxicosis,
hypoglycemia, stress)
, stenosis Correct Answer-most important determinant of resistance is
minimum ______ cross-sectional area
50-70 Correct Answer-coronary plaques that occupy less than ____% of
the vessel diameter are often called "non-obstructive" and rarely produce
ischemia or angina. They don't cause symptoms are are often discovered
late.
small Correct Answer-small/large plaques have a rich lipid core and thin
fibrous cap, are more prone to rupture and acute thrombus formation,
and are potentially lethal
70 Correct Answer-plaques that cause <___% stenosis are obstructive.
Increased physical exertion cannot be accommodated, as autoregulation
has reached a ceiling
diastole Correct Answer-the heart is perfused during systole/diastole?
decreases Correct Answer-increased HR increases/decreases time spent
in diastole
higher Correct Answer-patients with SIHD might require blood
transfusions at a higher/lower hemoglobin level compared to those
without?
acute chronic stable ischemia Correct Answer-SIHD is not an _____
event but rather manifests as either ____ _____ exertional angina or
_____ without clinical symptoms
women metabolic Correct Answer-microvascular angina is more
common in ____ and those with _____ syndrome
vasospasm Correct Answer-coronary _____ represents a form of angina
that results from an increase in coronary vascular tone that can either
occur in normal or diseased vessels
vasospastic Correct Answer-Prinzmetal's angina is a form of _____
angina that does not involve atherosclerotic placque
atherosclerotic LV comorbidities symptoms Correct Answer-prognosis
of pts with SIHD is related to extent of _____ disease, presence of ____
dysfunction, and the presence of other ______. Severity of angina
______ can be useful in determining prognosis.
increase demand decrease supply Correct Answer-the pathophysiology
of SIHD is driven by an (increase/decrease) in myocardial oxygen
______ (supply/demand) in the setting of a fixed (increase/decrease)
myocardial oxygen ______ (supply/demand)
,atherosclerotic plaque Correct Answer-etiology of fixed decrease in
myocardial oxygen supply is long-standing, well-developed ____
______
are not Correct Answer-episodes of angina in SIHD are/are not
associated with ruptured atherosclerotic plaque and thrombus formation
does not Correct Answer-in SIHD, vessel lumen size does/does not
acutely change
HR contractility tension Correct Answer-major determinants of oxygen
demand include ____, myocardial _____, and intramyocardial wall
_____***
size BP muscle mass Correct Answer-intramyocardial wall tension, the
leading contributor to increased MVO2, is directly related to the ____ of
the ventricular cavity and ____ and indirectly to the ventricular ____
_____
physical exertion Correct Answer-rapid increase in ____ ____ is
particularly likely to precipitate angina
HR Correct Answer-generally, events/conditions that cause an increased
_____ can precipitate angina (i.e. fever, exposure to cold, thyrotoxicosis,
hypoglycemia, stress)
, stenosis Correct Answer-most important determinant of resistance is
minimum ______ cross-sectional area
50-70 Correct Answer-coronary plaques that occupy less than ____% of
the vessel diameter are often called "non-obstructive" and rarely produce
ischemia or angina. They don't cause symptoms are are often discovered
late.
small Correct Answer-small/large plaques have a rich lipid core and thin
fibrous cap, are more prone to rupture and acute thrombus formation,
and are potentially lethal
70 Correct Answer-plaques that cause <___% stenosis are obstructive.
Increased physical exertion cannot be accommodated, as autoregulation
has reached a ceiling
diastole Correct Answer-the heart is perfused during systole/diastole?
decreases Correct Answer-increased HR increases/decreases time spent
in diastole
higher Correct Answer-patients with SIHD might require blood
transfusions at a higher/lower hemoglobin level compared to those
without?
