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Pharm 1140 Exam 1 Questions and Answers Graded A+ What is the definition of pharmacodynamics? Pharmacodynamics is the study of how drugs affect the body, including mechanisms of action and the relationship between drug concentration and effect. How does bioavailability impact drug effica...

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  • October 5, 2024
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  • 2024/2025
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Pharm 1140 Exam 1 Questions and
Answers Graded A+
What is the definition of pharmacodynamics?


✔✔Pharmacodynamics is the study of how drugs affect the body, including mechanisms of

action and the relationship between drug concentration and effect.




How does bioavailability impact drug efficacy?


✔✔Bioavailability refers to the proportion of a drug that reaches the systemic circulation and is

available to have an effect on the body.




What is the role of the liver in drug metabolism?


✔✔The liver is the primary organ responsible for metabolizing drugs, often converting them into

less active or more easily excreted forms.




What is a prodrug?


✔✔A prodrug is an inactive substance that is metabolized in the body to become an active drug.




Why is protein binding important in pharmacology?


1

, ✔✔Protein binding affects how much of a drug is free to exert its effects, as only unbound drugs

are active in the body.




How do drug-receptor interactions influence therapeutic effects?


✔✔Drug-receptor interactions determine the intensity and duration of a drug's effects, depending

on how well the drug binds to its target receptors.




What is the difference between agonists and antagonists?


✔✔Agonists activate receptors to produce a biological response, while antagonists block

receptors and prevent a response.




How does the blood-brain barrier affect drug distribution?


✔✔The blood-brain barrier restricts the passage of certain drugs into the brain, protecting it from

potentially harmful substances but also limiting the treatment of central nervous system

conditions.




What is the therapeutic index, and why is it important?


✔✔The therapeutic index is the ratio between a drug’s toxic dose and its effective dose,

indicating its safety margin.


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