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N398 Exam 1 Pharmacology & Pathophysiology questions with correct answers $16.99   Add to cart

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N398 Exam 1 Pharmacology & Pathophysiology questions with correct answers

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Aspirin Correct Answer-NSAID Anti-inflammatory, Analgesia, Anti-platelet Non-selective irreversible inhibitor of COX1/2, inhibits production of prostaglandins GI Effects, renal impairment, toxicity, bleeding Other NSAIDS, glucocorticoids, anticoagulants DONT USE IN PEDs- REYES S...

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  • October 21, 2024
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N398 Exam 1 Pharmacology & Pathophysiology
questions with correct answers
Aspirin Correct Answer-NSAID


Anti-inflammatory, Analgesia, Anti-platelet


Non-selective irreversible inhibitor of COX1/2, inhibits production of
prostaglandins


GI Effects, renal impairment, toxicity, bleeding


Other NSAIDS, glucocorticoids, anticoagulants


DONT USE IN PEDs- REYES SYNDROME


Oxycode/Morphine Correct Answer-Opioid analgesic


Pain relief
(OxycodoneGreater effect than morphine)


Mimic action of endogenous opioid peptides at mu receptor


Respiratory depression, constipation, orthostatic hypotension, urinary
retention, cough suppression, biliary colic emesis, sedation, euphoria

,CNS depressants, anticholinergic drugs, hypotensive drugs


Can develop tolerance to sedation and respiratory depression but not
constipation.
Antidote: naloxone


Naloxone Correct Answer-Opioid antagonist


Opposite effect of opioids


Used to reverse respiratory depression in cases of opioid overdose


Cause wakefulness


Clinical outcome: patient breathing


Amoxicillin (Penicillin) Correct Answer-Aminopenicillin


Useful against gram +/- organisms, some anaerobic coverage


Cell wall synthesis inhibitor - leading to cell death

,Hypersensitivity reactions, diarrhea


Caution with oral contraceptive use, use a backup method


Broad spectrum, given orally
May take with food
Renally eliminated: adjust dose in renal dysfunction


Amoxicillin + Clavulanic acid (Penicillin) Correct Answer-
Aminopenicillin, Beta- lactamase inhibitor


Covers gram +/- organisms as well as some anaerobic organisms.
Extends spectrum to cover organisms that are beta-lactamase producing.
Ex. H.influenzae


Cell wall synthesis inhibitor


Hypersensitivity reactions, diarrhea, abdominal cramps


Caution with oral contraceptive use, use a backup method


Adjust dose in renal dysfunction. May take with food

, Piperacillin + Tazobactam (A Penicillin) Correct Answer-
Antipseudomonal penicillin, beta- lactamase inhibitor


Broad spectrum coverage (g+, g-, anaerobes)
Covers Pseudomonas aeruginosa


Cell wall synthesis inhibitor


Hypersensitivity reactions, diarrhea


Adjust dose in renal dysfunction. Educate on signs and symptoms of
c.diff
Only IV


Cephalexin Correct Answer-Oral 1st generation Cephalosporin


Mainly active against gram + (skin flora)


Cell wall synthesis inhibitor


Nausea, vomiting, diarrhea. More common to have reaction to penicillin
than cephalosporin


Renally eliminated: adjust dose. Check kidneys. May take with food

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