Guyton 25 Body Fluid Compartments: ECF and ICF Final Exam Study Test.
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EECF
Institution
EECF
Guyton 25 Body Fluid Compartments: ECF and ICF Final Exam Study Test.
How do the kidneys help maintain homeostasis? - CORRECT ANSWER Maintain relatively constant volume and stable composition of body fluids:
1. regulate body fluid volume (via output/ retention)
2. regulate constituents of EC f...
Guyton 25 Body Fluid Compartments:
ECF and ICF Final Exam Study Test.
How do the kidneys help maintain homeostasis? - CORRECT ANSWER Maintain relatively constant
volume and stable composition of body fluids:
1. regulate body fluid volume (via output/ retention)
2. regulate constituents of EC fluid (via output/ retention)
3. acid-base balance
Composition of fluid in the body - CORRECT ANSWER Total body water: 60% BW
ICF (2/3 TBW): 40% BW
ECF (1/3 TBW): 20% BW
Interstitial fluid: 15% BW
Plasma: 5%
Other constituents: transcellular (<1%): synovial, peritoneal, pericardial, intraocular, cerebrospinal
Which types of fluid are more readily exchanged constituents? - CORRECT ANSWER Plasma and
interstitial fluid
Passing across from ECF to ICF requires pumps, and channels
What drives water movement? - CORRECT ANSWER Starling forces (hydrostatic)
Osmotic forces
What percent of body weight is blood? - CORRECT ANSWER 7% bodyweight
, What differences in composition are there between plasma and interstitial fluid? - CORRECT ANSWER
Protein concentration only
Capillary membranes are highly permeable to water and ions, and less permeable to proteins
How permeable is the intra- and extra-cellular space? - CORRECT ANSWER Highly permeable to water,
not permeable to most other electrolytes in the body
How is fluid volume measured/ estimated - CORRECT ANSWER Indicator/ dilution principal
- place indicator substance in compartment, allw to disperse evenly, and analyze the substance dilution.
c1v1=c2v2
v2 = c1v1/c2
How are specific compartments determined? - CORRECT ANSWER Total body water: 3-H2O, 2-H2O
ECF - 22-Na, 124-L-iothalamate, inulin -- substances that disperse inp lasma and interstitial fluid but do
not penetrate cell membrane -- aka Sodium space, inulin space
Plasma volume- 125-albumin, Evans blue dye -- not readily passed through capillarymembranes; remains
in vascular system
What compartment cannot be measured directly? - CORRECT ANSWER Intracellular fluid -- must be
calculated from Total H2O - ECF
How do you calculate blood volume? - CORRECT ANSWER Blood volume = (plasma volume)÷ (1-
hematocrit)
How do you calculate interstitial volume? - CORRECT ANSWER Interstitial volume = ECF-plasma volume
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