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  • November 26, 2024
  • Unknown
  • 2024/2025
  • Class notes
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courtneyfocht
Endocrine glands & functions
Pituitary
Anterior – largest part
Hormone effect on target stimulus
for release
ACTH - stimulates adrenal cortex to release aldosterone & cortisol
- stress
FSH -sperm production; ovarian follicles for eggs -GnRH
LH -testicular; ovulation (release of egg) -GnRH
GH - during anabolic metabolism, cartilage growth -Normal
growt/dev.
& catabolism of fat. BGL & insulin effects.
PRL -stimulates production of breast milk -estrogen,
preg/nursing
TSH -stim. Thyroid to release T3 & T4 -thyroid needs

Posterior
Hormone effect on target stimulus for
release
ADH -add h20 back into body; tells kidney to reabsorb -  BP, Pain,
High osmolality
H20. Of blood.
Oxytocin -maternity: stimulate contraction & lactation of -L&D of
Newborn; infant BF.
Breast milk
Thyroid
T3 & T4 T4T3 (active thyroid hormone) w/ the help of TSH (thyroid stimulating
hormone)

 Hypothalamus releases TRH (thyrotropin-releasing hormone) THEN CAUSES the anterior
pituitary to release TSH
 Thyroid stimulates & then releases T3(active thyroid hormone), T4(thyroid hormone),
Calcitonin (puts TONS of Ca IN bone)
 Calcitonin TONES down the Ca in the blood put putting the Ca BACK into the bone.

Hypothyroidism: Low T3 & T4; High TSH
Hashimoto (low & slow); low dietary iodine; **Pituitary tumor!!; thyroidectomy
S/S: constipation; hypotension

Hyperthyroidism: High T3 & T4; Low TSH
#1 cause is Graves disease; Iodine excess; Levothyroxine excess
S/S: enlarged thyroid, HTN

*dietary iodine found in salt makes T3 & T4; so iodine deficiency causes hypothyroidism

TEST TIP: always focus on what the levels are for T3 & T4 first!! TSH will always be the opposite of
T3 & T4!
**TSH is just trying to SLOW down the HYPER or AMP up the HYPO

Parathyroid
PTH: parathyroid hormone Negative Feedback Loop: Ca+ HIGH  PTH
SHUTS OFF
Memory trick: PTH Puts The calcium High Ca+ LOW PTH
TURNS ON
PC – Parathyroid & Calcium (9-10.5)
PTH is HIGH = Ca is HIGH How is Ca  in blood? RIB
PTH is LOW = Ca is LOW R – Renals reabsorb Ca+ from urine
I – intestines (GI) absorption (help of Vit. D activation)
Hypoparathyroidism: = hypocalcemia B – Bone (into the blood)

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