Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
b| b| b| b| b| b| b| b| 1
Edition
Chapter 01: Drug Definitions, Standards, and Information Sources
b| b| b| b| b| b| b|
Willihnganz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
b| b| b| b| b| b| b| b|
MULTIPLE CHOICE b|
1. Which name identifies a drug listed by the US Food and
b| b| b| b| b| b| b| b| b| b|
Drug Administration (FDA)?
b| b| b|
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C b|
The official name is the name under which a drug is listed
b| b| b| b| b| b| b| b| b| b| b|
by the FDA. The brand name, or trademark, is the name
b| b| b| b| b| b| b| b| b| b| b|
given to a drug by its manufacturer. The nonproprietary,
b| b| b| b| b| b| b| b| b|
or generic, name is provided by the United States
b| b| b| b| b| b| b| b| b|
Adopted Names Council.
b| b| b|
DIF: Cognitive Level: Knowledge REF: p. 9 b| b| b | b|
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective
b| b| b| b| b| b| b|
Care Environment TOP: Nursing Process Step: Assessment CON:
b| b| b| b | b| b| b|
Patient Education
b| b|
2. Which source contains information specific to nutritional supplements?
b| b| b| b| b| b| b|
a. USP Dictionary of USAN & International Drug Names
b| b| b| b| b| b| b|
b. Natural Medicines Comprehensive Database b| b| b|
c. United States Pharmacopoeia/National Formulary (USP NF)
b| b| b| b| b|
d. Drug Interaction Facts b| b|
ANS: C b|
United States Pharmacopoeia/National Formulary contains information specific to nutritional
b| b| b| b| b| b| b| b|
supplements. USP Dictionary of USAN & International Drug Names is a compilation of
b| b| b| b| b| b| b| b| b| b| b| b| b|
drug names, pronunciation guide, and possible future FDA approved drugs; it does not
b| b| b| b| b| b| b| b| b| b| b| b| b|
include nutritional supplements. Natural Medicines Comprehensive Database contains
b| b| b| b| b| b| b| b|
evidence-based information on herbal medicines and herbal combination products; it does not
b| b| b| b| b| b| b| b| b| b| b|
include information specific to nutritional supplements. Drug Interaction Facts contains
b| b| b| b| b| b| b| b| b| b|
comprehensive information on drug interaction facts; it does not include nutritional
b| b| b| b| b| b| b| b| b| b| b|
supplements.
b|
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3 b| b| b | b| b|
NAT: NCLEX Client Needs Category: Physiological Integrity
b| b | b| b| b| b| b|
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
b | b| b| b| b| b| b| b|
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
b| b| b| b| b| b| b| b| b| b| b| b| b|
a. Drug Facts and Comparisons b| b| b|
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
b| b| b| b| b| b| b| b| b|
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
b| b| b| b| b| b| b| b| 2
Edition
b. Drug Interaction Facts b| b|
c. Handbook on Injectable Drugs b| b| b|
d. Martindale—The Complete Drug Reference b| b| b|
ANS: A b|
Drug Facts and Comparisons contains drug monographs that describe all drugs in
b| b| b| b| b| b| b| b| b| b| b|
a therapeutic class. Monographs are formatted as tables to allow comparison of
b| b| b| b| b| b| b| b| b| b| b| b|
similar products, brand names, manufacturers, cost indices, and available dosage
b| b| b| b| b| b| b| b| b| b|
forms Online version is available.
b| b| b| b| b|
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 b| b| b | b| b| b|
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
b | b | b| b| b| b| b| b|
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
b | b| b| b| b | b| b| b| b| b| b|
4. Which drug reference contains monographs about virtually every single-entity drug available
b| b| b| b| b| b| b| b| b| b|
in the United States and describes therapeutic uses of drugs, including approved and
b| b| b| b| b| b| b| b| b| b| b| b| b|
unapproved uses?
b| b|
a. Martindale: The Complete Drug Reference b| b| b| b|
b. AHFS Drug Information b| b|
c. Drug Reference b|
d. Drug Facts and Comparisons b| b| b|
ANS: B b|
AHFS Drug Information contains monographs about virtually every single-entity drug
b| b| b| b| b| b| b| b| b|
available in the United States and describes therapeutic uses of drugs, including approved and
b| b| b| b| b| b| b| b| b| b| b| b| b| b|
unapproved uses.
b| b|
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 b| b| b | b| b| b|
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
b | b | b| b| b| b| b| b|
TOP: Nursing Process Step: Planning
b | CON: Safety | Patient Education | Clinical Judgment
b| b| b| b | b| b| b| b| b| b|
5. Which online drug reference makes available to healthcare providers and the public a
b| b| b| b| b| b| b| b| b| b| b| b|
b| standard, comprehensive, up-to-date look up and downloadable resource about medicines?
b| b| b| b| b| b| b| b| b|
a. American Drug Index b| b|
b. American Hospital Formulary b| b|
c. DailyMed
d. Drug Reference b|
ANS: C b|
DailyMed makes available to healthcare providers and the public a standard,
b| b| b| b| b| b| b| b| b| b|
comprehensive, up-to-date look up and downloadable resource about medicines. The
b| b| b| b| b| b| b| b| b| b|
American Drug Index is not appropriate for patient use. The American Hospital
b| b| b| b| b| b| b| b| b| b| b| b|
Formulary is not appropriate for patient use. The drug reference is not appropriate for
b| b| b| b| b| b| b| b| b| b| b| b| b| b|
patient use.
b| b|
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 OBJ: 3 b| b| b | b| b| b| b| b|
NAT: NCLEX Client Needs Category: Physiological Integrity
b| b | b| b| b| b| b|
TOP: Nursing Process Step: Implementation
b| b| b| b|
CON: Safety | Patient Education | Clinical Judgment
b | b| b| b| b| b| b|
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
b| b| b| b| b| b| b| b| b| b| b| b| b| b|
a. Federal Food, Drug, and Cosmetic Act (1938) b| b| b| b| b| b|
b. Durham Humphrey Amendment (1952) b| b| b|
b |
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
b| b| b| b| b| b| b| b| b|
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
b| b| b| b| b| b| b| b| 3
Edition
c. Controlled Substances Act (1970) b| b| b|
d. Kefauver Harris Drug Amendment (1962) b| b| b| b|
ANS: A b|
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the
b| b| b| b| b| b| b| b| b| b| b| b| b| b|
safety of all drugs before marketing. Later amendments and acts helped tighten FDA
b| b| b| b| b| b| b| b| b| b| b| b| b|
control and ensure drug safety. The Durham Humphrey Amendment defines the kinds of
b| b| b| b| b| b| b| b| b| b| b| b| b|
drugs that cannot be used safely without medical supervision and restricts their sale to
b| b| b| b| b| b| b| b| b| b| b| b| b| b|
prescription by a licensed practitioner. The Controlled Substances Act addresses only
b| b| b| b| b| b| b| b| b| b| b|
controlled substances and their categorization. The Kefauver Harris Drug Amendment
b| b| b| b| b| b| b| b| b| b|
ensures drug efficacy and greater drug safety. Drug manufacturers are required to prove to
b| b| b| b| b| b| b| b| b| b| b| b| b| b|
the FDA the effectiveness of their products before marketing them.
b| b| b| b| b| b| b| b| b| b|
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3 b| b| b | b| b| b|
OBJ: 5 NAT: NCLEX Client Needs Category: Physiological
b | b| b| b| b| b|
Integrity TOP: Nursing Process Step: Assessment
b| b| b | b| b| b|
CON: Safety | Patient Education | Evidence | Health Care Law
b | b| b| b| b| b| b| b| b| b|
7. Which classification does meperidine (Demerol) fall under?
b| b| b| b| b| b|
a. I
b. II
c. III
d. IV
ANS: B b|
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead
b| b| b| b| b| b| b| b| b| b| b| b| b| b| b| b|
to severe psychological and physical dependence. Schedule I drugs have high potential for
b| b| b| b| b| b| b| b| b| b| b| b| b|
abuse and no recognized medical use. Schedule III drugs have some potential for abuse.
b| b| b| b| b| b| b| b| b| b| b| b| b| b|
Use may lead to low to moderate physical dependence or high psychological dependence.
b| b| b| b| b| b| b| b| b| b| b| b| b|
Schedule IV drugs have low potential for abuse. Use may lead to limited physical or
b| b| b| b| b| b| b| b| b| b| b| b| b| b| b|
psychological dependence.
b| b|
DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: 2 b| b| b | b| b|
NAT: NCLEX Client Needs Category: Safe, Effective Care
b| b| b| b| b| b| b| b|
Environment
b|
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
b | b| b| b| b | b| b| b| b| b|
8. Which action would the FDA take to expedite drug development and approval for an outbreak
b| b| b| b| b| b| b| b| b| b| b| b| b| b|
b| of smallpox?
b|
a. List smallpox as a health orphan disease.
b| b| b| b| b| b|
b. Omit the preclinical research phase. b| b| b| b|
c. Extend the clinical research phase. b| b| b| b|
d. Fast track the investigational drug.
b| b| b| b|
ANS: D b|
Once the Investigational New Drug Application has been approved, the drug can receive
b| b| b| b| b| b| b| b| b| b| b| b|
highest priority within the agency, which is called fast tracking. A smallpox outbreak
b| b| b| b| b| b| b| b| b| b| b| b| b|
would become a priority concern in the world. Orphan diseases are not researched in a
b| b| b| b| b| b| b| b| b| b| b| b| b| b| b|
priority manner. Preclinical research is not omitted. Extending any phase of the research
b| b| b| b| b| b| b| b| b| b| b| b| b|
would mean a longer time to develop a vaccine. The FDA must ensure that all phases of the
b| b| b| b| b| b| b| b| b| b| b| b| b| b| b| b| b| b|
preclinical and clinical research phase have been completed in a safe manner.
b| b| b| b| b| b| b| b| b| b| b| b|
DIF: Cognitive Level: Knowledge b| b| REF: b| b| p. 7 b| OBJ: b | 5
b |
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
b| b| b| b| b| b| b| b| b|
, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
b| b| b| b| b| b| b| b| 4
Edition
NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
b| b| b| b| b| b| b| b|
TOP: Nursing Process Step: Assessment
b| b | b| b| b|
CON: Health Care Law | Health Care Policy | Infection | Care Coordination
b | b| b| b| b| b| b| b| b| b| b| b|
9. Which statement is true about over-the-counter (OTC) drugs?
b| b| b| b| b| b| b|
a. They are not listed in the USP NF.
b| b| b| b| b| b| b|
b. A prescription from a healthcare provider is needed.
b| b| b| b| b| b| b|
c. They are sold without a prescription.
b| b| b| b| b|
d. They are known only by their brand names.
b| b| b| b| b| b| b|
ANS: C b|
OTC medications do not require a prescription. A variety of names, both generic and trade,
b| b| b| b| b| b| b| b| b| b| b| b| b| b|
can be used for individual drugs sold OTC. OTC drugs are listed in the USP NF.
b| b| b| b| b| b| b| b| b| b| b| b| b| b| b| b|
Prescription drugs require an order by a health professional who is licensed to prescribe,
b| b| b| b| b| b| b| b| b| b| b| b| b| b|
such as a physician, nurse practitioner, physician assistant, or dentist.
b| b| b| b| b| b| b| b| b| b|
DIF: Cognitive Level: Comprehension REF: p. 2 OBJ: 2 b| b| b | b| b|
NAT: NCLEX Client Needs Category: Physiological Integrity
b| b | b| b| b| b| b|
TOP: Nursing Process Step: Planning
b | CON: Patient Education b| b| b| b | b|
10. Which is the most authoritative reference for medications that are injected?
b| b| b| b| b| b| b| b| b| b|
a. Martindale: The Complete b| b|
b. Handbook on Injectable Drugs b| b| b|
c. DailyMed
d. Handbook of Nonprescription Drugs b| b| b|
ANS: B b|
The Handbook on Injectable Drugs is the most comprehensive reference available on the
b| b| b| b| b| b| b| b| b| b| b| b|
topic of compatibility of injectable drugs. It is a collection of monographs for more than 300
b| b| b| b| b| b| b| b| b| b| b| b| b| b| b| b|
injectable drugs that are listed alphabetically by generic name.
b| b| b| b| b| b| b| b| b|
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3 b| b| b | b| b|
NAT: NCLEX Client Needs Category: Physiological Integrity
b| b | b| b| b| b| b|
TOP: Nursing Process Step: Assessment CON: Clinical Judgment | Safety
b | b| b| b| b | b| b| b|
11. Which statement is true about Lomotil?
b| b| b| b| b|
a. Abuse potential for this drug is low. b| b| b| b| b| b|
b. Psychological dependency is likely. b| b| b|
c. There is a high potential for abuse. b| b| b| b| b| b|
d. This drug is not a controlled substance.
b| b| b| b| b| b|
ANS: A b|
Lomotil, a Schedule V drug, has an abuse potential of limited physical or psychological
b| b| b| b| b| b| b| b| b| b| b| b| b|
dependence liability compared with drugs in Schedule IV. Because abuse potential is low
b| b| b| b| b| b| b| b| b| b| b| b| b|
with a Schedule V drug, a prescription may not be required. Psychological dependency is not
b| b| b| b| b| b| b| b| b| b| b| b| b| b| b|
likely with a Schedule V drug. Schedule V drugs are classified as controlled substances.
b| b| b| b| b| b| b| b| b| b| b| b| b| b|
DIF: Cognitive Level: Knowledge REF: p. 5 Box 1.1 OBJ: 2 b| b| b | b| b| b| b|
NAT: NCLEX Client Needs Category: Physiological Integrity
b| b | b| b| b| b| b|
TOP: Nursing Process Step: Assessment CON: Clinical Judgment | Safety | Patient Education
b | b| b| b| b | b| b| b| b| b| b|
