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Class notes BIOL 6351

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Boost Your Research with This Comprehensive Toll-Like Receptors Reference Table! Elevate your immunological studies with this meticulously designed document detailing Toll-Like Receptors (TLRs). Ideal for scientists, researchers, and students, this easy-to-read table includes receptor locations,...

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  • February 23, 2025
  • 1
  • 2024/2025
  • Class notes
  • Prof. dong
  • Lecture 2 (toll-like receptor family)
All documents for this subject (1)
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pragyashekhawat
Receptor Receptor Ligand Source of the Expressing cells
location Ligand
TLR1 Cell surface Bacterial lipoprotein Gram positive Macrophages
bacteria and Dendritic cells
myobacteria B cells
TLR2 Cell surface Lipoteichoic acid Gram positive Macrophages
Bacterial cell wall components bacteria and Neutrophils
myobacteria Dendritic cells
Mast cells
TLR3 Endosomal Double-stranded RNA dsRNA viruses Dendritic cells
surface B cells
TLR4 Cell surface LPS Gram negative Macrophages
bacteria Neutrophils
Dendritic cells
Mast cells
B cells
TLR5 Cell surface and Flagellin Flagella of bacteria Macrophages
intestinal Dendritic cells
epithelial cells
TLR6 Cell surface Diacyl lipopeptides Gram positive Macrophages
bacteria and fungi Mast cells
B cells
TLR7 Endosomal Single-stranded RNA ssRNA viruses Macrophages
surface Dendritic cells
B cells
TLR8 Endosomal Single-stranded RNA ssRNA viruses Macrophages
surface Phagocytosed bacterial RNA Dendritic cells
Mast cells
TLR9 Endosomal CpG oligodeoxynucleotide Bacteria and DNA Macrophages
surface DNA viruses Dendritic cells
B cells
TLR10 Cell surface Unknown Unknown Unknown
TLR11/12 Endosomal Profilin (from Toxoplasma) Toxoplasma gondii, Macrophages
surface uropathogenic Dendritic cells
bacteria
TLR13 Endosomal Bacterial ribosomal RNA Bacterial ribosomal Macrophages
surface RNA Dendritic cells

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