Full Revision Bundle for medical Microbiologists and Nurses

Plastic medical equipment that has a low melting point would best be sterilized using what technique? - ***gas sterilization Protein synthesis inhibitors affect which primary target? - ***ribosomes If irradiation sterilizes by targeting DNA. What is the correct ranking of what irradiation would b...

Coupled transcription and translation - Ribosomes bind mRNA while mRNA is still being created, so that translation begins while transcription is still occurring - Advantage of lacking a nucleus Translation initiation - - Initiation factors bind ribosome to the ribosome binding site known as the ...

Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer) - ***AD MLH1, MSH2, MSH6, PMS2 gene mutation causing DNA mismatch repair 3-2-1 rule: cancer in 3 family members, within 2 generations, and in 1 relative under 50 Most common hereditary form of colorectal cancer Associated with gastric, ...

Lesch-Nyhan Syndrome: what causes it and what are manifestations? - ***HGPRT deficiency in purine salvage pathway (this enzyme normally converts hypoxanthine to IMP and guanine to GMP). This deficiency leads to excessive Uric acid production and de novo purine synthesis. It is X linked recessi...

Lesch-Nyhan syndrome - type of deficiency - symptoms - ***HGPRT deficiency Gout, intellectual disability, aggressive behavior, hyperuricemia, dystonia Kartegener's syndrome - dynein arm defect in cilia - ***Situs inversus, chronic sinusitis, bronchiectasis, infertility, sperm immotile, fal...

A 35-year-old man who is an undocumented immigrant is diagnosed with tuberculosis. Despite feeling ill, he did not previously seek medical care because he could not afford to lose time at work. He pleads with the physician not to report the diagnosis to anyone because he is afraid he will be dep...

Chagas Disease - ***Caused by Trypanosoma cruzi parasite passed in the feces of Reduviidae/kissing bug Penetrates broken skin or intact mucous membranes forming a pseudocyst releasing inflammatory infiltrates into myocytes; stains with Giemsa & Wright Romana sign occurs when portal of entry is t...

Name diseases of glycogenolysis (Types 1, 2, 3 & 5) 1 = von Gierke, 2 = Pompe, 3 = Cori, 5 = McArdle Mallory bodies Alcoholic liver disease: intermediate filaments of hepatocyte cytoskeleton Damage to liver in hemochromatosis is due to what? Free radicals Hemosiderin an iron-storage protein p...

Staphylococcus - ***gram + clusters streptococcus - ***gram + chains or pairs bacillus anthracis - ***gram + rod clostridia (tetani, botulinum, perfringens, difficile) - ***gram + obligate anaerobic rods group B - ***Strep. agalactiae group A - ***Strep. pyogenes a-hemolytic bacteria - ***gram...