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Summary Anti-Ulcer Drugs

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This is a summary of the background of indigestion, GORD, stomach and duodenal ulcers along with the pharmacological treatments used to manage these conditions









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Uploaded on
February 7, 2016
Number of pages
5
Written in
2015/2016
Type
Summary

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Drugs used to treat indigestion, stomach and duodenal ulcers and
GORD

Indigestion (dyspepsia):
 Symptoms include: lower abdominal pain, belching, nausea, bloating, distention, all
of which are usually provoked by eating.
 Affects 40% (40m) of the UK population annually
 Only 1.2m consult their GP
 With 12,000 being referred for endoscopy
 If over the age of 45, gastric cancer should be ruled out by endoscopy


Stomach and duodenal ulcers:
1) Epidemiology -
 Is usually a benign ulcer disease of the upper GI tract
 Ratio of duodenal to gastric ulcers is 4:1
 There is a wide age distribution and peak incidence is around middle age
 These type of ulcers are more common in males

2) Risks –
 Stomach ulcers are most likely to become malignant
 Duodenal ulcers are usually benign




3) Symptoms –
 Upper abdominal pain, appetite loss, weight loss, anaemia, blood in faeces
 Symptoms often relieved by milk, eating, rest and antacids

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