UNE Medical Biochemistry Midterm Review| 88 Questions| With Complete Solutions
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Module
UNE Biochemistry
Institution
University Of New England (UNE
)
A family presents for genetic counseling. The couple has two female children who are alive and well; however, their infant son recently died in the nursery with severe hemolysis (lysis of red blood cells) and jaundice. The wife recalls she lost a brother in infancy with severe hemolysis, induced af...
une medical biochemistry midterm review| 88 questi
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University of New England (UNE
)
UNE Biochemistry
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UNE Medical Biochemistry Midterm Review| 88
Questions| With Complete Solutions
A family presents for genetic counseling. The couple has two
female children who are alive and well; however, their infant
son recently died in the nursery with severe hemolysis (lysis of
red blood cells) and jaundice. The wife recalls she lost a brother
in infancy with severe hemolysis, induced after a viral infection.
The physician suspects a glucose-6-phosphate dehydrogenase
deficiency, this would result in a deficiency in which of the
following compounds in red blood cells? correct answer:
Ribose and NADPH
A patient presents to the emergency department with lactic
acidosis. A deficiency in thiamine (TPP) is suspected and this
will be consistent with a decrease in the activity of following
enzymes? correct answer: Transketolase
Galactose 1-phosphate is initially converted to glucose 1-
phosphate and requires which of the following compounds?
correct answer: UDP-Glucose
Which of the following cofactors is required for transketolase
activity? correct answer: Thiamine diphosphate
Aldolase B facilities a reaction that cleaves fructose 1-phosphate
into two 3-carbon molecules that will enter glycolysis as which
of the following compounds? correct answer: Glyceraldehyde
3-phosphate
, High levels of activity of the non-oxidative portion of the
pentose phosphate pathway will directly produce intermediates
of which of the following pathways? correct answer: Glycolysis
The major regulatory step of the pentose phosphate pathway is
catalyzed by which enzyme? correct answer: Glucose 6-
phosphate dehydrogenase
Insulin stimulates fatty acid synthesis in the liver. These fatty
acids are transported to the adipose tissue as which of the
following? correct answer: VLDL particles
A young woman goes to work without eating breakfast and skips
lunch. In this scenario, which of the following pathways is
providing substrates used to generate ATP in the liver? correct
answer: Free fatty acids
Caffeine is a natural inhibitor of phosphodiesterase. If you were
to consume a large amount of coffee you would likely see a
prolonged response to which of the following stimulants or
hormones? correct answer: Glucagon
A teenage female presenting with lack of menstruation
(amenorrhea) is found to have a dysfunctional steroid receptor
characteristic of androgen insensitivity syndrome. Which of the
following statements accurately describes steroid hormones?
correct answer: They enhance transcription when bound to
receptors
Steroid hormones bind which of the following types of
receptors? correct answer: Intracellular receptors
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