NBME CBSE, ANSWERED-Bulbus cordis - Smooth parts (outflow tract) of left and right ventricles
endocardial cushions - Atrial septum, membranous interventricular septum; AV and semilunar valves
neural crest
left horn of the sinus venosus - coronary sinus
posterior, sub cardinal, and supra...
NBME CBSE, ANSWERED
Bulbus cordis - Smooth parts (outflow tract) of left and right ventricles
endocardial cushions - Atrial septum, membranous interventricular septum; AV
and semilunar valves
neural crest
left horn of the sinus venosus - coronary sinus
posterior, sub cardinal, and supra cardinal veins - IVC
Right common cardinal vein and right anterior cardinal vein - SVC
Right horn of sinus venosus - Smooth part of right atrium (sinus venarum)
Patent foramen ovale - failure of septum primum and septum secundum to fuse
after birth
Transposition of the great vessels
Tetralogy of Fallot
Persistent truncus arteriosus - Conotruncal abnormalities associated with failure of
neural crest cells to migrate
ductus venosus - connects the umbilical vein to the inferior vena cava, bypassing
the liver
becomes ligamentum venosum
phrenic nerve - innervates the diaphragm and pericardium
S3 heart sound - Increased ventricular filling pressure (e.g., mitral regurgitation,
HF), common in dilated ventricles
,normal in kids and pregnant women
S4 heart sound - atrial kick late diastole, right before S1
Mg sulfate - for torsades de pointe, hypokalemia (can lengthen QT and cause
torsades), and pre-eclampsia (prevent seizures)
Romano-Ward syndrome - -Congenital long QT syndrome
-Autosomal dominant, pure cardiac phenotype (no deafness).
Jervell and Lange-Nielsen syndrome - -Congenital long QT syndrome
-Autosomal recessive, sensorineural deafness
Brugada syndrome - -Autosomal dominant disorder affecting Na channels most
common in Asian males.
-ECG pattern of pseudo-right bundle branch block and ST elevations in V1-V3
(anterior ventricular septum)
-inc risk of ventricular tachyarrhythmias and sudden cardiac deatgh
Prevent SCD with implantable cardioverter-defibrillator (ICD).
Wolff-Parkinson-White Syndrome - Most common type of ventriuclar pre-
excitation sydnrome. Abnormal fast accessory conduction pathway from atria to
venricle bypasses the rate-slowing AV node causing a delta wave and widening
QRS with shortened PR interval. Could lead to a reentrant circuit and
suprvaventicular tachy.
First degree AV block - - PRI >5 boxes/.20 sec (200 msec)
- Fixed but prolonged PRI
(consistent but long)
- normally get bradycardia here
second degree AV block mobitz type 2 - -PR interval is constant
, -atrial conduction to ventricle is intermittent: dropped QRS without increasing PR
interval length
-disease below AV node in His bundle
may progress to 3rd degree/complete AV block
Second Degree AV Block Mobitz Type 1 (wenckebach) - Progressive lengthening
of pr interval leading to dropped QRS
third degree AV block - The atria and Ventricles are totally dissociated.
-So, the QRSs and the P waves have no relation to each other.
PCWP - 4-12 mmHg
est of LA pressure
Williams Syndrome - a genetic condition characterized by mental retardation in
most regards but surprisingly good use of language relative to their other abilities,
elfin facies
Chromosome 7
assoc with supravalvular aortic stenosis
DiGeorge Syndrome - Maldevelopment of 3 and 4 pharyngeal pouches, fascial
dysmorphia, cardiac shunt (trunks arteriosus, tetralogy of Fallot), lack of T-cells,
undeveloped paracortex
Corneal arcus - Lipid deposits in the cornea. Common in the elderly, but appears
earlier in life with hypercholesterolemia
Stanford A aortic dissection - Dissection of the ascending aorta
Tx with surgery
Stanford B aortic dissection - Dissection of the descending aorta below the level o
the left subclavian artery
Tx: Beta Blockers then vasodilators
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