BIOL 2200 PATHO WEEK 3: CASE STUDY 2 LATEST UPDATE GRADED A+

BIOL 2200 PATHO WEEK 3: CASE STUDY 2 LATEST UPDATE GRADED A+ Describe the difference in the histology of the tumour if it had been assessed as a adenoma rather than adenocarcinoma An adenoma is a benign tumour: lost ability to control proliferation the growth is slow the cells are still well differentiated and organized, they also do not invade beyond their capsule do not metastisize. An adenocarcinoma is a malignant tumour: more rapid growth rate loss of differentiation and no longer organized, there is a lack of capsule so they can invade near by structures they are able to metastize. List three other characteristics of an adenocarcinoma that would differenciate it from a benign tumour Rapid growth No capsule Can metastisize Explain Ms.Peters' clinical manifestations that initially brought her to see her doctor She suffers from anemia, in the lab results she has a decrease in her RBC count. She was at 3.5 million/cubic mm while the normal is 4.2-5.4 million. This is why she was feeling weak and fatigue Why was she asked about a heavy menstrual flow? She couldve been losing a lot of blood from her period which could explain the low RBC count What does "fecal occult blood" mean? Why did the positive fecal occult blood result in Ms.Peters undergoing a colonoscopy? How does the result of the colonoscopy explain her initial clinical manifestations It means theres blood in feces. Colonoscopy can tell if theres inflammation, tumour or bleeding of the rectum and colon. She had a tumour in her colon which makes it hard for the waste products to get by What is the significance of the serum CEA level? What would a subsequent rise in this value possible indicate? Abnormal Carcinoembryonic antigen in adults can indicate cancer. If there was a rise after a patient has been treated, it means