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Lecture notes

Essential Notes for Respiratory Medicine Finals

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Author credentials - Top scorer medical school finals University of Sheffield in 2022 - London Internal Medicine Trainee - Passed MRCP part 1 and part 2 - PGdiploma in medical education Features - All you need for final year medical school exams - Digital file editable Word document - PD...

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  • June 2, 2024
  • 107
  • 2023/2024
  • Lecture notes
  • Respiratory
  • Respiratory medicine finals
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eugenechen
Respiratory for finals
Created by: Dr Chen




JUNE 1, 2024

,Contents


Oxygen therapy ........................................................................................................................................................................................................... 3

Pulmonary function tests ............................................................................................................................................................................................ 6

Acute bronchitis ........................................................................................................................................................................................................ 11
Pag
Chronic Obstructive Pulmonary Disease (COPD) ...................................................................................................................................................... 13
|1
Smoking cessation .................................................................................................................................................................................................... 21

Asthma ...................................................................................................................................................................................................................... 22

Acute asthma attack ................................................................................................................................................................................................. 27

Consolidation on CXR ................................................................................................................................................................................................ 30

Pneumonia ................................................................................................................................................................................................................ 31

Cryptogenic organizing pneumonia .......................................................................................................................................................................... 36

Pulmonary eosinophilia ............................................................................................................................................................................................ 38

Diffuse Alveolar Haemorrhage Syndromes ............................................................................................................................................................... 40

Allergic BronchoPulmonary Aspergillosis .................................................................................................................................................................. 42

Interstitial Lung Disease (ILD) ................................................................................................................................................................................... 45

Idiopathic Pulmonary Fibrosis (IPF) .......................................................................................................................................................................... 47

Extrinsic Allergic Alveolitis (EEA) / Hypersensitivity pneumonitis ............................................................................................................................. 49

Pneumoconiosis ........................................................................................................................................................................................................ 52

Progressive massive fibrosis (PMF) ........................................................................................................................................................................... 53

Bronchiectasis ........................................................................................................................................................................................................... 56

Cystic fibrosis ............................................................................................................................................................................................................ 59

Sarcoidosis .............................................................................................................................................................................................................. 62

Pulmonary Hypertension .......................................................................................................................................................................................... 65

Pleural Effusion ......................................................................................................................................................................................................... 70

Pneumothorax .......................................................................................................................................................................................................... 73

Tension pneumothorax - medical emergency ........................................................................................................................................................... 76

Pulmonary Embolism (PE) ......................................................................................................................................................................................... 85

Pharyngitis/Tonsillitis ................................................................................................................................................................................................ 89

Sinusitis ..................................................................................................................................................................................................................... 90

Epiglottitis ................................................................................................................................................................................................................. 91

Whooping cough ....................................................................................................................................................................................................... 92

Acute laryngo-tracheobronchitis (Croup) ................................................................................................................................................................. 93

,Tuberculosis ............................................................................................................................................................................................................. 94

Respiratory failure .................................................................................................................................................................................................... 99

Acute Respiratory Distress Syndrome (ARDS) / Acute lung injury .......................................................................................................................... 100

Methaemoglobinaemia........................................................................................................................................................................................... 104

Carbon monoxide poisoning ................................................................................................................................................................................... 105
Pag
|2

, Oxygen therapy


Always note when prescribing oxygen:
- Type of oxygen delivery system (nasal cannula, Venturi mask)
- Inspired oxygen concentration or flow rate
- Target oxygen saturation
- Monitoring
o Observe patient’s colour, RR, level of consciousness, O2 sats, ABG Pag
o Patient with non rebreath mask (NRBM) should have continuous pulse oximetry
|3
Management:
Presentation of type 2 respiratory failure:
- All acutely unwell patients = reservoir mask at 15 l/min to maintain optimal
- 67yo women
tissue oxygenation and prevent organ failure
- Drowsy
o Hypoxia is more dangerous than hypercapnia and will cause
- Cough green sputum
patients to have cardiac arrest if severe or prolonged.
- Past medical history of asthma
o Exceptions where O2 is only needed if hypoxic – only give
- Smokes 15 cigarettes a day
additional oxygen if O2 sats below target range
▪ MI, ACS On examination:
▪ Stroke - Oxygen sats 95%
▪ Obstetric emergencies - Alert
▪ Anxiety related hyperventilation - Widespread wheezing – lower airway, high
- Acutely unwell patient at risk of CO2 retention with no history of pitched
respiratory acidosis e.g. COPD, bronchiectasis, NMD, morbid obesity - No crackles
o Prior to availability of blood gases = NRBM oxygen - pH low
o If ABG shows CO2 retention = use a 28% Venturi mask at 4l/min + - Normal PaO2
aim for an oxygen saturation of 88-92% - High PaCO2 level
o If ABG shows normal pCO2 = adjust target range to 94-98% - Elevated bicarbonate levels

Management:
Oxygen saturation targets
- Type 2 respiratory failure
• Acutely ill patients = 94-98%
- Treatment:
• Patients at risk of hypercapnia (e.g. COPD patients) = 88-92%
o Cautious oxygenation
• Oxygen should be reduced in stable patients with satisfactory oxygen o Bronchodilators, steroids and antibiotics
saturation
o 1 hour of medical treatment then
repeat ABG
Oxygen delivery system
o if don’t respond, give NIV
- Simple Face Masks
o Deliver an oxygen concentration between 35-60%, with a flow rate of 5–10L/min
o Minimum flow rate should be 5 l/min (to eliminate the build-up of exhaled CO2).
o Cant measure how much O2 patient is receiving, worst way to deliver
o For any given flow rate, the inspired oxygen concentration achieved will vary, as it depends upon the rate and depth of the
patient’s breaths and the patient's minute volume.
▪ A high minute volume will lower the inspired oxygen concentration, as increased inspiratory flow rates will cause an
in-drawing of air so diluting the oxygen delivered
▪ Conversely slower breathing will increase the inspired oxygen concentration.
o In patients requiring prolonged oxygen therapy on the ward, humified oxygen should be considered – this uses a similar face
mask, but an additional humidification device helps to prevent drying of the patient’s secretions, which may significantly
worsen their respiratory problem.

- Nasal cannulae
o Capable of delivering an inspired oxygen concentration of between 24-50% depending on the flow rate of the oxygen (1-6
L/min).
o The inspired oxygen concentration achieved will vary, as it depends upon the oxygen flow rate and the depth and rate of the
patient’s breaths
o Maximum flow rate is 4 l/minute because higher rates can cause nasal mucosal drying and epistaxis

- Venturi masks
o Deliver precisely controlled percentages of high flow oxygen from 24-60%
o The valves are colour coded according to the percentage of oxygen delivered
o Useful in patients where a specific oxygen concentration is required for example in COPD patients.

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