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Patho Final Exam #1 (Cell Adaptation & Inflammation, Genes, Obesity, and Cancer) 2024

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Patho Final Exam #1 (Cell Adaptation & Inflammation, Genes, Obesity, and Cancer) 2024

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clincal manifestations - ✅✅-signs and symptoms of disease
Etiology - ✅✅-cause of disease
Morphology - ✅✅-study of form

Pathogenesis - ✅✅-development of disease

Pathophysiology - ✅✅-the study of how disease processes affect the function of the body

atrophy - ✅✅-to waste away

Hyoertrophy - ✅✅-increase in cell size

hyperplasia - ✅✅-increase in number of cells

metaplasia - ✅✅-Mature cell type is replaced by a different mature cell type

Dysplasia - ✅✅-abnormal development

Apoptosis - ✅✅-programmed cell death

necrosis - ✅✅-tissue death

bradykinin - ✅✅-most potent pain stimulus known

cellular chemotaxis - ✅✅-During the cellular phase of inflammation, a chemical signal from
microbial agents, endothelial cells, and WBCs attracts platelets and other WBCs to the site
of injury.

✅✅-proteins secreted by cytotoxic T cells to aid in antigen destruction
cytokines -

Exudate - ✅✅-fluid that accumulates in a wound; may contain serum, cellular debris,
bacteria, and white blood cells

histamine - ✅✅-A chemical that is responsible for the symptoms of an allergy
inflammation - ✅✅-a localized response to an injury or to the destruction of tissues

mast cells - ✅✅-Cells that release chemicals (such as histamine) that promote
inflammation.

margination - ✅✅-neutrophils cling to the walls of capillaries in the injured area
Neutrophils - ✅✅-A type of white blood cell that engulfs invading microbes and contributes
to the nonspecific defenses of the body against disease.

, phagocytes - ✅✅ -a type of cell within the body capable of engulfing and absorbing
bacteria and other small cells and particles.

primary intention - ✅✅ -primary union of the edges of a wound, progressing to complete
scar formation without granulation

secondary intention - ✅✅ -Wound healing where edges can't be easily approximated and
wound fills with granulation

tertiary intention -✅✅ -The wound is purposely left open due to heavy infection or
contamination
initially cleaned, debrided and observed
(Tissue Graft, Stage 4 Pressure ulcer with necrotic tissue and infection)

vascular permeability - ✅✅-allows entry of cells into tissue
Aneuploidy -✅✅-Abnormal number of chromosomes.
Autosomes - ✅✅-Any chromosome that is not a sex chromosome

carrier - ✅✅-A person whose genotype includes a gene that is not expressed in the
phenotype.

chromosome - ✅✅ -a threadlike structure of nucleic acids and protein found in the nucleus
of most living cells, carrying genetic information in the form of genes.

dominant - ✅✅-Describes a trait that covers over, or dominates, another form of that trait.
genotype - ✅✅-genetic makeup of an organism

incidence - ✅✅-The number or rate of new cases of a particular condition during a specific
time.

karyotype - ✅✅-A display of the chromosome pairs of a cell arranged by size and shape.
multifactorial inheritance - ✅✅-an interaction between genes and the environment that
contributes to a phenotype or trait

Mutation -✅✅-A change in a gene or chromosome.
Nondisjunction - ✅✅-Error in meiosis in which homologous chromosomes fail to separate.

Phenotype - ✅✅-physical characteristics of an organism

prevalence - ✅✅-The number or proportion of cases of a particular disease or condition
present in a population at a given time.

recessive - ✅✅-An allele that is masked when a dominant allele is present

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