First-generation cephalosporins are commonly used for prophylaxis against
infection in surgical patients.
Cefuroxime, a second-generation cephalosporin, is used to treat pneumonia caused
by H. influenza, Klebsiella, pneumococci, and staphylococci.
, Third-generation cephalosporins are used to treat gram-negative pathogens.
Also able to penetrate CSF - useful in the treatment of meningitis.
Fourth-generation cephalosporins are extensively used to treat healthcare- and
hospital-associated pneumonia, particularly those caused by the resistant bacterium
Pseudomonas aeruginosa.
Fifth-generation cephalosporins are used to treat MRSA.
Carbapenems - Answer: Imipenem
Meropenem
Ertapenem
Doripenem
Carbapenem usage - ANSWER: beta-lactam
Very broad spectrum.
Not active against MRSA.
imipenem - A carbapenem
Active against most bacterial infections.
Gram-positive and gram-negative cocci
Bacilli are
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