NWHSU Histology Exam 1 Review Questions
And Answers
The inner nuclear membrane on the nuclear envelope is supported by: Nuclear Lamina
During mitosis what causes the disassembly of nuclear envelope? Phosphorylation of the
lamin
Steps of creating chromosomes -Double helix DNA wound around 8 histone proteins
assemble into nucleosomes(structural unit of chromatin packaging)
-these chromatins are fibrils which fold together with each other to make fibers. (tight fold is
heterochromatin, loose fold is euchromatin)
-fibers will further condense to form chromosomes
Karyotype contains 22 pairs of autosomes and 1 pair of sex chromosomes (XX or XY)
All somatic cells have: 46 chromosomes (diploid 2n)
All germs cells(after meiosis) have 23 chromosomes (haploid 1n
,NWHSU Histology Exam 1 Review Questions
And Answers
What is used in karyotype analysis to stop diving cells? Colchicine
What stage are the cells stopped at in karyotype analysis? Metaphase( because the
chromosomes are maximally condensed)
Metaphase chromosomes appear as: sister chromatids
Trisomy of the 21st chromosome is called Down Syndrome
Trisomy of the 18th chromosome is called Edwards Syndrome
Trisomy of the 13th chromosome is called Patau Syndrome
What is Kleinefelter Syndrome? XXY of the sex chromosomes
What is Turner Syndrome? Only having an X chromosome (X0)
, NWHSU Histology Exam 1 Review Questions
And Answers
A person with an XX karyotype has how many sex chromatins? 1
A person with an XXXX karyotype has how many sex chromatins? 3
A person with an XY karyotype has how many sex chromatins? 0
In neutrophils sex chromatins appear as? bar bodies(drum stick appendage)
A nucleotide is made up of? nitrogenous base (purine/pyrimidine), deoxyribose sugar and
a phosphate group
nucleosides are made up of? nitrogenous base(purine/pyrimidine) and a deoxyribose sugar
Nucleotides are linked together by: phosphodiester bond
Notable purines: Adenine(A) & Guanine(G)
And Answers
The inner nuclear membrane on the nuclear envelope is supported by: Nuclear Lamina
During mitosis what causes the disassembly of nuclear envelope? Phosphorylation of the
lamin
Steps of creating chromosomes -Double helix DNA wound around 8 histone proteins
assemble into nucleosomes(structural unit of chromatin packaging)
-these chromatins are fibrils which fold together with each other to make fibers. (tight fold is
heterochromatin, loose fold is euchromatin)
-fibers will further condense to form chromosomes
Karyotype contains 22 pairs of autosomes and 1 pair of sex chromosomes (XX or XY)
All somatic cells have: 46 chromosomes (diploid 2n)
All germs cells(after meiosis) have 23 chromosomes (haploid 1n
,NWHSU Histology Exam 1 Review Questions
And Answers
What is used in karyotype analysis to stop diving cells? Colchicine
What stage are the cells stopped at in karyotype analysis? Metaphase( because the
chromosomes are maximally condensed)
Metaphase chromosomes appear as: sister chromatids
Trisomy of the 21st chromosome is called Down Syndrome
Trisomy of the 18th chromosome is called Edwards Syndrome
Trisomy of the 13th chromosome is called Patau Syndrome
What is Kleinefelter Syndrome? XXY of the sex chromosomes
What is Turner Syndrome? Only having an X chromosome (X0)
, NWHSU Histology Exam 1 Review Questions
And Answers
A person with an XX karyotype has how many sex chromatins? 1
A person with an XXXX karyotype has how many sex chromatins? 3
A person with an XY karyotype has how many sex chromatins? 0
In neutrophils sex chromatins appear as? bar bodies(drum stick appendage)
A nucleotide is made up of? nitrogenous base (purine/pyrimidine), deoxyribose sugar and
a phosphate group
nucleosides are made up of? nitrogenous base(purine/pyrimidine) and a deoxyribose sugar
Nucleotides are linked together by: phosphodiester bond
Notable purines: Adenine(A) & Guanine(G)
