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DNA Replication and the Genetic Code Summary

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Summary of DNA replication and the degenerate genetic code.

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  • January 1, 2025
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  • 2015/2016
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3.9 DNA Replication and the
Genetic Code
First review @October 17, 2023

Practise Q's Done

cells divide for growth or repair of tissues

two daughter cells produced by mitosis are genetically identical and diploid

before cells begin to divide they prepare, this stage is interphase

this is when DNA is replicated

Semi-conservative replication
for DNA to be replicated, the hydrogen bonds between base pairs must be broken to
expose one strand of DNA that can be copied

DNA replication is described as semi-conservative (half the same) since the two new
DNA helices formed are each made of one old and one new strand of DNA

roles of enzymes in replication

DNA Helicase— travels along the polynucleotide chains and breaks the hydrogen
bonds between base pairs to leave one strand of DNA that can be replicated

DNA polymerase only travels in the 3’ to 5’ direction which results in a ‘lagging’ and
a ‘leading’ strand— only the leading strand can have DNA replicated from it as the
DNA unwinds and the lagging strand has to be replicated backwards in sections
called Okazaki fragments which are later joined together by DNA ligase

DNA polymerase— catalyses the formation of phosphodiester bonds between free
nucleotides to reform the sugar-phosphate backbone




3.9 DNA Replication and the Genetic Code 1

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