PCEUT (Department of Pharmaceutics ) Bundle Set

In theory, in a dispersed system, if cohesive force is greater than adhesive force, phase separation will occur. - Answer True The higher the HLB value of a surfactant, the more hydrophobic the surfactant is. - Answer False In general, hydrophilic surfactants tend to be used to formulate O...

The salting-out effect is attributed to a competition between solute molecules for the solvent - Answer TRUE Packaging of a drug is usually not considered to be part of compounding of a dosage form - Answer FALSE Solutions are homogenous liquid mixtures in which the solute is dispersed thr...

Dispersed systems - Answer When one component (drug) is distributed more or less uniformly throughout the second component (medium), the mixture is called a dispersion system in which surfactants are often added. particle diameter in molecular dispersions (i.e. solutions) - Answer < 1.0 nm...

Stability - Answer Extent to which a drug product retains, within specified limits, throughout its period of storage and use, the same properties and characteristics that it possessed at the time of its manufacture Forced degradation studies - Answer Studying effects of very extreme condition...

tablets - Answer solid dosage forms containing drug substances with or without suitable diluents and prepared either by compression or molding Compression - Answer large scale Molding - Answer small scale Compressed tablets - Answer prepared by single compression with no special coa...

melt, dissolve, soften - Answer Suppositories, inserts, and sticks are solid dosage forms and/or intended for insertion into body orifices where they ___________, __________, and/or __________. False - Answer True or False: There may be only one API dispersed in a suitable base and molded or ...

modified-release dosage forms - Answer alter the timing, rate and/or the location of release of the drug substances to achieve a desired therapeutic objective or better patient compliance timing rate location - Answer what do modified-release dosage forms alter about drug release therape...

Suspensions definition - Answer Liquid preparations that consist of solid particles Dispersed through out a liquid phase in which particles are not soluble. Product Types - Answer Oral suspensions Topical Suspensions Sterile suspensions for injection Oral suspensions - Answer Aluminum ...

T/F: Drugs that form MI complexes with CYP enzymes (e.g., macrolide antibiotics) can cause the irreversible loss of active enzyme. - Answer T T/F: When considering an interaction between the CYP3A inhibitor ritonavir and voriconazole, the magnitude of change in voriconazole AUC can be strongly ...

Percutaneous Absorption: Topical Drug Administration for Local or Systemic Effect - Answer Percutaneous absorption is the process by which drug passes into and/or through the skin after application to the surface of the skin. Equivalent terms include: • topical drug administration • dermal d...

Ointments are prepared by two general methods: ___ and ___ - Answer incorporation fusion Levigation - Answer triturating a powder drug with a solvent in which it is insoluble to reduce its particle size ___, a general method of ointment preparation, involves mixing the ingredients of t...

Radiopharmacy - Answer radiopharmaceuticals prepared for human use and therefore strict QC and safe handling of radiopharmaceuticals must be maintained Radiopharmacy is the _______ recognized pharmacy subspecialty - Answer first Nuclear Medicine - Answer use of radioactive compounds for ...

Antibodies and RNA-based therapeutics belong to a new class of therapeutics called "biologics". - Answer True Dosage form of a medication usually has little to do with clinical effectiveness of the drug. - Answer False The "Pharmacokinetics" of a drug refers to the time course of drug ...

Cisplatin MOA - Answer •Nephrotoxicity•Ototoxicity•Motor & sensory peripheral neuropathy•N/V Cisplatin toxicity - Answer •Nephrotoxicity•Ototoxicity•Motor & sensory peripheral neuropathy•N/V Cisplatin treatment for SE - Answer •Infusion of normal saline to keep Cl conc ...