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UNE CHEM 1005 Midterm Study Guide Questions With Complete Solutions

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What enzyme is used by the gluconeogenic pathway but NOT in the glycolytic pathway? correct answer: Phosphoenolpyruvate Carboxykinase PEPCK Newborn screening results show a biotinidase deficiency in a 2 day old infant. The deficiency impairs the infant's ability to reuse and recycle biotin. Due...

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Biochemistry Final Exam: UNE CHEM 1005 Weeks 9-15 Questions With Complete Solutions

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Control of Fatty Acid Synthesis vs. Oxidation correct answer: When Insulin is HIGH --> fatty acid synthesis occurs When Glucagon is HIGH --> lipolysis, fatty acid B-oxidation, ketogenesis occur **These never happen at the same time! Lipolysis correct answer: Process of releasing free ...

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UNE BioChem 1005 Final Exam Questions With Complete Solutions

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Somatostatin reduces the secretion of both glucagon and insulin through which of the following mechanisms? a. Somatostatin activates an activator G-protein b. Somatostatin activates MAPK cascade c. Somatostatin activates an inhibitory G-protein d. Somatostatin uses Ca+2 as a downstream signal...

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UNIT 1 UNE CHEM 1005 Questions With Complete Solutions

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Hemoglobin binds oxygen with a greater affinity in the: correct answer: R state Hemoglobin bound to heme is termed a holoprotein. The heme or porphoryin ring is required for oxygen binding and it is termed a: correct answer: prosthetic group Alpha helices and beta sheets are primarily stabil...

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UNE CHEM 1005 Midterm Study Guide Questions With Complete Solutions

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What enzyme is used by the gluconeogenic pathway but NOT in the glycolytic pathway? correct answer: Phosphoenolpyruvate Carboxykinase PEPCK Newborn screening results show a biotinidase deficiency in a 2 day old infant. The deficiency impairs the infant's ability to reuse and recycle biotin. Due...

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UNE CHEM 1005: MEDICAL BIOCHEMISTRY FINAL EXAM QUESTIONS WITH COMPLETE SOLUTIONS

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Carnitine palmitoyl transferase correct answer: - transfers acyl groups from CoA to carnitine & vice versa - inhibited by malonyl-CoA ketone bodies correct answer: - acetoacetate, β-hydroxybutyrate, acetone - oxidized as fuel source in extreme fasting d-3-hydroxybutyrate dehydrogenase cor...

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UNE CHEM 1005 Unit 3 Exam Questions With Complete Solutions

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Which of the following lipoproteins is responsible for carrying cholesterol from peripheral tissues (i.e skeletal muscle) back to the liver? correct answer: HDL What is the primary role of LCAT (Lecithin-cholesterol acyltransferase)? correct answer: To esterify cholesterol transported by HDL ...

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UNE Biochem 1005 Unit 2 exam Questions With Complete Solutions

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1. Pyruvate dehydrogenase kinase catalyzes a reaction that results in which of the following? correct answer: The phosphorylation and inactivation of E1 subunit (pyruvate dehydrogenase complex 1. Which of the following intermediates is an allosteric activator of pyruvate kinase? correct answer: ...

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UNE CHEM 1005 Module 15 Questions With Complete Solutions

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During exercise the pathways of ____________________ and ______________________ are integrated as means of providing energy and reducing NH4+ levels. correct answer: BCAA catabolism and purine degradation The primary role of glutamine in the brain is to provide substrate for the synthesis of whi...

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UNE BIOCHEM 1005 WEEK 1 QUESTIONS WITH COMPLETE SOLUTIONS

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What are the four different protein structures? correct answer: 1. Primary 2. Secondary 3. Tertiary 4. Quaternary What is the primary structure of a protein? correct answer: a linear sequence of amino acids in polypeptide chains which is written from the amino terminus (N-terminus) to the ca...

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UNE CHEM 1005 Midterm Review Questions With Complete Solutions

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Which of the following best describes tertiary structure? correct answer: Interactions between alpha helices and beta sheets to form a domain Movement of ammonia from an amino acid to an alpha-keto acid involves a family a enzymes best categorized as which of the following? correct answer: Tran...

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CHEM 1005 Week 1 Practice Evaluation Questions With Complete Solutions

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Covalent catalysis is used by many enzymes to cleave peptide bonds. Which of the following amino acids would not facilitate this type of catalysis? (Think of the structure of the R-group of these amino acids) correct answer: Valine The R-group on valine does not have an active group to particip...

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CHEM 1005 Midterm Questions With Complete Solutions

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Changes in the physiological variables listed below can alter the affinity of hemoglobin for oxygen. Which of the following will lower the affinity of hemoglobin for oxygen? correct answer: Increase in 2,3 bisphosphoglycerate (BPG) A decreased affinity will increase the rate of oxygen delivery t...

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CHEM 1005 Final Review Questions With Complete Solutions

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In the fasted state, fatty acyl-CoA are transported across the mitochondrial membrane. The transport of fatty acids via carnitine palmitoyl transferase I (CPTI) can be directly inhibited by which of the following compounds? a. Malonyl CoA b. Carnitine c. Acetyl CoA d. Palmitate correct answ...

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CHEM 1005: Medical Biochemistry Unit 3 Module pre-quizzes and quizzes Questions with complete solutions

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Which of the following is the major regulation point for transport of fatty acids into the mitochondria? correct answer: carnitine acyltransferase I The primary activation of triacylglycerol mobilization in adipocytes is through __________ of the enzyme ____________. correct answer: phosphoryla...

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UNE BioChem 1005 Unit 3 Review| 154 Questions| With Complete Solutions

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Which of the following is the major regulation point for transport of fatty acids into the mitochondria? correct answer: carnitine acyltransferase I The primary activation of triacylglycerol mobilization in adipocytes is through __________ of the enzyme ____________. correct answer: phosphoryla...

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UNE BioChem 1005 - Module 8 - Carbohydrate Metabolism

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The second messenger in the signaling cascade initiated by glucagon is: correct answer: cAMP Explanation: The second messenger for glucagon is cAMP. Review Module 2 GPCR signaling cascades When insulin is bound to its receptor an autophosphorylation event occurs and the IRS binds these phosphor...

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UNE CHEM 1005 Unit 2 Review Questions With Complete Solutions

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Which oxidation reaction requires the coenzyme FAD because it involves oxidation of a carbon-carbon single bond to a double bond? correct answer: oxidation of succinate to fumarate Pyruvate dehydrogenase kinase will facilitate which of the following reactions? correct answer: The pyruvate dehyd...

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UNE BioChem 1005 - Unit 2 review| 154 Questions| With Complete Solutions

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Which of the following reactions is commonly used to replenish intermediates of the citric acid cycle? correct answer: glutamate --> ketoglutarate Which of the following statements is true regarding the activity of the ribonuceltide reductase? correct answer: The enzyme is required to conver...

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UNE Biochem 1005 Exam 1| 110 Questions| With Complete Solutions

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Cysteine is a nonessential amino acid as it can be synthesized from: correct answer: Methionine All transaminiation reactions require: correct answer: Pyridoxal Phosphate Synthesis of Tyrosine requires: correct answer: Tetrahydrobiopterin (BH4) PKU results from a heritable defect in: cor...

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UNE CHEM 1005 Module 12 Questions With Complete Solutions

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Under cellular conditions when cholesterol is low, which of the following is a true statement regarding the sterol response element binding protein ? correct answer: It will be associated with the the sterol response element (SRE) in the DNA Secondary bile salts are generated by bacterial modifi...

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UNE Chem 1005 Final Questions With Complete Solutions

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In the fasted state, fatty acyl-CoAs are transported across the mitochondrial membrane. The transport of fatty acids via carnitine palmitoyl transferase 1 can be directly inhibited by which of the following compounds? correct answer: Malonyl-CoA An individual is on a hunger strike and has not ea...

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CHEM 1005 Final Exam Review Questions With Complete Solutions

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What is the role of adipose in metabolism? correct answer: Storage of triacylglycerols as a source of energy that can be released as FFAs under fasted state conditions; other roles include body weight homeostasis, coagulation, immunity, vascular tone control, appetite regulation, glucose/lipid meta...

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UNE CHEM 1005 Module 10 Questions With Complete Solutions

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Cleavage of fructose 1-phosphate into dihydroxyacetone-phosphate and glyceraldehyde 3-phosphate is facilitated by which enzyme? correct answer: aldolase Red blood cells lack mitochondria, therefore glucose is primarily oxidized to which of the following compounds? correct answer: lactate Gal...

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BIOCHEM 1005 UNIT 4 STUDY QUESTIONS WITH COMPLETE SOLUTIONS

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A 16-year-old girl complains that she often feels light-headed and dizzy just before lunch at school. She tells you that she often does not eat breakfast. She almost always feels better after lunch. You explain to her that she is experiencing hypoglycemia. Under these conditions, you would expect: c...

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