BCH 403 Exam 1 Questions with Complete Solutions

(T/F) A biochemical reaction, without a catalyst or thermodynamic coupling, takes 50 years to reach a state of equilibrium. Without more information, we cannot make a determination on either the value of the Keq constant or the positive or negative value of the ΔG of the reaction. Correct Answer-False (T/F) Due to its small size, the amino acid glycine can be found in tight turns in a protein structure. Correct Answer-True (T/F) The ΔG of a reaction is defined as the energy required to bring the concentration of reactants and products to equal concentration. Correct Answer-False (T/F) One strength of nuclear magnetic resonance spectroscopy is that it can detect multiple conformations of proteins and one of its limitations is that protein must contain certain isotopes. Correct Answer-True (T/F) A single residue mutation to an enzyme decreases its rate constant by one half. This means the reaction now occurs more slowly. Correct Answer-True (T/F) The hydrophobic packing of non-polar residues is thermodynamically favorable because of both the hydrophobic effect and a larger number of weak van der Waals interactions. Correct Answer-True