NR 507 midterm Exam Questions with Correct Answers

Hypersensitivity: Type 1 - Answer--Mediated IgE -inflammation due to mast cell degranulation -anaphylactic, asthma, hay fever treatment: epinephrine Hypersensitivity: Type 2 - Answer--Cytotoxic reaction: tissue specific -binds to the antigen ON THE CELL SURFACE -macrophages are primary effectors cells involved cause tissue damage or alter function Hypersensitivity 2 - Answer--Graves Disease (hyperthyroidism) -alters function not destroy -blood transfusions reaction- transfused erythrocytes are destroyed by agglutination or lysis -drug allergies -hemolytic anemia Hypersensitivity: type 3 - Answer--Not organ specific -antibody binds to soluble antigen OUTSIDE THE CELL SURFACE that was released into the blood or bodily fluids, and the complex is then deposited in the tissues Hypersensitivity: Type 3 - Answer--rheumatoid arthritis -Systemic Lupus Erythematosus (SLE) -Raynaud's Hives (urticaria) - Answer-Hypersensitivity Type 1 First responders to innate the immune system - Answer-Neutrophils Allergic contact dermatitis - Answer-Hypersensitivity Type IV Type 2 cytotoxic hypersensitivity mediated by: - Answer--IgG IgM -macrophages are primary effort cells - Serum Sickness - Answer-type 3 hypersensitivity Hypersensitivity IV, - Answer--is more of a delayed immune response. -mediated T-cells attack tissue directly (no antibodies)