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Virology Final Exam Review Questions with Correct Answers
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Virology Final Exam Review Questions with Correct Answers
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Virology Final Exam Review Questions with CorrectAnswers
1) Which of the following is not considered a cytopathic effect?
A) Syncytia
B) Presence of inclusion bodies
C) Cell shrinkage
D) Hemagglutination
E) Cell aggregation Correct Answer-D) Hemagglutination
2) Animal inoculation is the preferred method of cultivating viruses.
True OR False Correct Answer-FALSE
3) ____ refers to the ability of a virus to immortalize cells rather than
killing them. Correct Answer-Transformation
4) Which of the following is not one of modifications Rivers made to
Koch's original postulates?
A) Nucleic acid sequence of the virus present in all cases of infectious
disease
B) Isolation of virus from diseased hosts
C) Re-isolation of the same virus from an infected experimental host
D) Detection of a specific immune response to the virus
E) Proof of filterability Correct Answer-A) Nucleic acid sequence of the
virus present in all cases of infectious disease
,5) Influenza A virus is capable of causing red blood cells to agglutinate.
True or False Correct Answer-TRUE
6) Clinical virology laboratories routinely use reverse transcriptase-PCR
(RT-PCR) technology to amplify the genomes of RNA viruses. True OR
False Correct Answer-TRUE
7) The BSL-2 classification is reserved for laboratories that work with
infectious agents that have no vaccine or cure. True OR False Correct
Answer-FALSE
8) PCR and RT-PCR are used to monitor ____ during HIV and hepatitis
C infection in order to assess the efficacy of a chosen antiviral therapy.
Correct Answer-viral loads
9) Which assay can be performed to detect viral antigens in a specimen
as well as a patient's immune response to a virus?
A) Enzyme-linked immunosorbent assay
B)Polymerase chain reaction
C) Electron microscopy
D) TCID 50
E) Shell vial technique Correct Answer-A) Enzyme-linked
immunosorbent assay
, 10) Plaque reduction assays are the gold standard for directly measuring
the efficacy of an antiviral drug on viral infection in tissue culture. True
OR False Correct Answer-TRUE
1) Due to low childhood vaccination rates and political unrest, ____
remains one of the last remaining polio-endemic countries accounting
for the majority of wild-type poliovirus infections. Correct Answer-
Pakistan
2) Initiation of translation of the poliovirus polyprotein is dependent on
which of the following?
A) VP3
B) IRES
C) IPV
D) 5' m7G cap
E) CD155 Correct Answer-B) IRES
3) Enteroviruses are transmitted from person to person by an oral-fecal
route. True OR False Correct Answer-TRUE
4) Only a small percentage of poliovirus infections are asymptomatic.
True OR False Correct Answer-FALSE
5) Polio virus infection can be cured using anti-viral drugs. True OR
False Correct Answer-FALSE
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