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Medical Virology Questions with Correct Answers.
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Medical Virology Questions with Correct Answers.
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Medical Virology Questions with Correct AnswersVirus Correct Answer-Agents that pass through filters that trap bacteria.
Do not grow in culture.
Visualized with e- microscopy.
Obligate intracellular parasites that need a host cell to reproduce.
Very small (nm) compared to cells (10um) and bacteria (1um)
River's Postulates Correct Answer-1. Isolate virus from diseased hosts
2. Cultivation of virus in host cells
3. Proof of filterability
4. Production of similar disease when cultivated virus used to infect
experimental hosts.
5. Re-isolation of same virus from infected host.
6. Detection of specific immune response to virus.
The basic virus life cycle Correct Answer-1. attachment
2. internalization
3. uncoating
4. transcription/translation
5. replication
6. assembly
7. exit
Note - all use host translational machinery
, What's wrong with Koch's postulates? Correct Answer-1. Microbes in
organisms suffering from disease and not in those that are healthy - BUT
asymptomatic carriers exist
2. Microbe must be isolated and grown in pure culture - BUT some
cannot be grown this way
3. Cultured microbe should cause disease - BUT not all exposed
individuals become infected
4. Microbe must be re-isolated and identified as being the same as
original agent.
Types of viral structures Correct Answer-Icosahedral, helical, complex,
naked or enveloped
Role of capsid Correct Answer-To protect genome from nucleases in the
environment. Capsid often fragile, because not needed, will be shed
during uncoating. Contains other proteins, such as receptor or
attachment proteins.
Nucleocapsid Correct Answer-Capsid + associated genome.
Enveloped viruses Correct Answer-Surrounded by extra lipid bilayer
around the capsid. Bilayer stolen from the host cell's plasma or nuclear
membrane.
DNA-dependent DNA polymerases Correct Answer-Carry out DNA
replication in 5 --> 3 direction.
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