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NURS 2320 - Pharm I Review (Week 1.1) Questions with Correct Answers
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NURS 2320 - Pharm I Review (Week 1.1) Questions with Correct Answers
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NURS 2320 - Pharm I Review (Week 1.1) Questionswith Correct Answers
Drugs that attach but do not elicit a response are called, _____ Correct
Answer-antagonists
what is pharmacokinetics? Correct Answer-The study of what the body
does to drug molecules
What is pharmacodynamics? Correct Answer-The study of what the
drug does to the body
what are adverse effects? Correct Answer-A direct response to one or
more drugs that results in undesirable effects
What are toxicities? Correct Answer-Serious adverse effects; often an
extension of the drug's therapeutic effect
what are the four steps of pharmacokinetics? Correct Answer-
absorption, distribution, metabolism, & excretion (ADME)
what are the 7 factors that affect absorption of a drug? Correct Answer--
dosage and chemical makeup of drug
- route
- food or fluids
- acidity in the stomach
, - status of GI motility/blood flow (connected)
- warmth or coolness of the body
- surface area and contact time
what is perfusion? Correct Answer-blood flow to organs
What is bioavailability? Correct Answer-fraction of a medication that is
absorbed into the systemic circulation after the first pass effect
what is the first pass effect? Correct Answer-- liver metabolism of oral
medication
- some of the dosage is inactivated in the liver before it reaches the
general circulation and site of action
what are the three factors that affect drug distribution? Correct Answer--
water solubility
- lipid solubility
- degree to which a drug is protein bound
what is the name for drugs that are not bound to a protein? Correct
Answer-free drug
what are the six factors that affect metabolism? Correct Answer-- liver
function
- drug interactions
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