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MBI 405 bug parade || with Error-free Solutions.
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sterile locations of the body correct answers Blood, deep tissues, lungs, synovial fluid, and cytoskeletal fluid staphylococci characteristics (>6) correct answers Gram+; hardy facultative anaerobes; mesophilic (temp/pH); resistant to drying, salt (10%), heat; membrane: peptidoglycan is lysoz...

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  • September 17, 2024
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  • 2024/2025
  • Exam (elaborations)
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  • sterile locations of the body

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MBI 405 bug parade || with Error-free Solutions.
sterile locations of the body correct answers Blood, deep tissues, lungs, synovial fluid, and
cytoskeletal fluid

staphylococci characteristics (>6) correct answers Gram+; hardy facultative anaerobes;
mesophilic (temp/pH); resistant to drying, salt (10%), heat; membrane: peptidoglycan is
lysozyme-resistant but lysostaphin-sensitive, techoic acids trigger inflammation; MRSA and
VRSA

diseases caused by staphylococci (6) correct answers skin abscesses (on the surface); cellulitis
(in the tissues); hematogenous spread (bloodstream -> other tissues/BONE); toxin-mediated
diseases (TSS, food poisoning, bulbous impetigo); thrombophlebitis; UTIs

streptococci characteristics (7) correct answers Gram+; facultative anaerobe; ferments acids
(lactic, acetic, formic); fastidious for AAs, purines/pyrimidines, and vitamins; mesophilic
(temp/pH); oxygen-tolerant; peptidoglycan is lysozyme-resistant (sim to staph)

2 ways to classify streptococci correct answers hemolytic activity and lancefield groups

GAS diseases (normal AND severe) correct answers normal: pharyngitis (strep throat, scarlet
fever) and skin infections (impetigo, erysipelas, cellulitis)

severe: pneumonia, meningitis, endocarditis; NF; STSS;

post-infectious sequelae: rheumatic fever, glomerulonephritis

GBS diseases (5) correct answers neonatal bacteremia, meningitis, pneumonia AND adult
pneumonia or bacteremia

pneumococci characteristics (8) correct answers gram+; capsule w/MANY serotypes; alpha-
hemolytic; facultative anaerobe; ferment many acids; mesophilic (temp/pH); peptidoglycan is
lysozyme-resistant; have C-polysaccharide and M-like proteins

Diseases caused by pneumococci (3) correct answers otitis media (inflammation of the inner
ear); pneumonia w/bloody sputum and pulmonary pain; meningitis (most common cause)

bordetella characteristics (4) correct answers very small G-; have metachromatic granules; strict
aerobes; non-motile; non-invasive

bordetella diseases (3) correct answers pertussis (whooping cough, highly contagious, divided
into two stages); parapertussis; kennel cough in dogs

2 stages of bordetella pertussis correct answers prodromal: mild symptoms but most infectious
paroxysmal: uncontrollable coughing fits where you can't catch your breath

, bacillus characteristics (6) correct answers boxy gram+ rods; aerobes; spore-forming; non-
motile; mesophilic (temp/pH); have pathogenic plasmids (pXO1 and pXO2)

bacillus diseases (3) correct answers cutaneous, gastrointestinal (can become septicemic), and
inhalational (pulmonary, fast-killing)

yersinia characteristics (5) correct answers Gram-; facultative anaerobes; non-motile; mesophilic
(temp ONLY); plasmids and PAI for virulence

yersinia diseases (3) correct answers bubonic plague (black death), septicemic plague;
pneumonic plague
gastroenteritis! goes away after 4 days, underdiagnosed

legionella characteristics (5) correct answers faintly gram- but prefer silver stain; motile
(multiple polar flagella); obligate AEROBES; fastidious but slow lab growers; adapted to live
INSIDE cells

legionella diseases correct answers Legionnaires' disease (type of walking/multilobar
pneumonia) and Pontiac fever (resembles acute influenza w/severe muscle aches)

Mycoplasma characteristics correct answers lack cell wall but technically G+; 'fried egg' colony
formation; smallest genomes; fastidious: require purines/pyrimidines, AAs, and lipids; require
HOSTS to survive; intrinsically resistant to Abi's (bc of no cell wall); require motility to be
virulent (gliding machinery or attachment organelle)

Mycoplasma pneumoniae disease/sequelae (1;3) correct answers respiratory infections w/heavy
biofilm formation (walking pneumonia); post-infectious sequelae: Guillan-Barre syndrome,
encephalitis, and stevens johnson syndrome (skin rash)

M. hominus and U. urealytica diseases (3) correct answers vaginal bacteriosis/pelvic
inflammatory disease; non-gonococcal urethritis; post-partum fever in women

Mycobacteria characteristics (7) correct answers acid-fast; G+ but hard to gram stain; strict
aerobes; complex cell walls w/mycolic acids (super long side chains, thick cell wall); slow
growers; no known plasmids but have mycobacteriophages; can be non-resistant, MDR, or XDR

mycobacteria tuberculosis diseases correct answers pulmonary tuberculosis (#1 deadly infectious
disease globally) and chronic pulmonary disease (opportunistic, esp. in AIDS patients)

M. leprae/lepromatosis disease correct answers Hansen's disease (leprosy)

M. ulcerans disease correct answers ulcerative skin lesions

Listeria characteristics (7) correct answers Gram+; motility depends on external temp; grows
well from 1-42ºC; salt tolerant (bad for food preserving); non fastidious; beta-hemolytic;
microaerophilic facultative anaerobe (prefers a little O2)

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