100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
MBI 405: Bacillus || Questions and 100% Accurate Answers. $10.49   Add to cart

Exam (elaborations)

MBI 405: Bacillus || Questions and 100% Accurate Answers.

 5 views  0 purchase
  • Course
  • MBI 405: Bacillus
  • Institution
  • MBI 405: Bacillus

McCullough-Hyde Memorial Hospital Story correct answers -neck lesion was misdiagnosed as an abscess with cellulitis (died of septic shock) -blood culture 4 days later @ Christ Hospital= anthrax -it was confirmed to be anthrax at a meeting with Communicable Disease Center of the US Public Health S...

[Show more]

Preview 2 out of 5  pages

  • September 17, 2024
  • 5
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • MBI 405: Bacillus
  • MBI 405: Bacillus
avatar-seller
FullyFocus
MBI 405: Bacillus || Questions and 100% Accurate Answers.
McCullough-Hyde Memorial Hospital Story correct answers -neck lesion was misdiagnosed as
an abscess with cellulitis (died of septic shock)
-blood culture 4 days later @ Christ Hospital= anthrax
-it was confirmed to be anthrax at a meeting with Communicable Disease Center of the US
Public Health Service in Atlanta
-the source of contamination was hair-felt insulation made with imported goat hair that Hoffman
used during a hospital remodeling job

Biological Warfare & Bioterrorism Potential (building) correct answers -building 470 @ Fort
Detrick, MD aka Pilot Plant or The Tower
-false windows made it looks like barracks or an office building
-built by the US army biological warfare laboratories
-seven stories tall to accommodate 2-3 story tall fermenters
-decommissioned in 1970, demolished in 2003

Biological Warfare & Bioterrorism Potential (aircraft) correct answers -payload: spores (50kg)
from aircraft spreads > 20km
-if released in a 2 km band upwind of a city of 5,000,000
(morbidity & mortality: 500,000 at risk, 250,000 incapacitated, 100,000 dead

Postal Distribution (2001) correct answers -4 senators, NY Post, NBC
-22 cases (pulmonary, cutaneous, 5 deaths)
-PROPHYLAXIS: 10,000 people received ciprofloxacin (the newest antibiotic at the time)
-The FBI blamed Bruce Edwards Ivins, a scientist who worked at the government's biodefense
labs at Fort Detrick (he was working on anthrax vaccines)
-he had an obsession with KKG sorority
-misspelled penicillin on the letter and said Allah is Great- which is an incorrect saying

General Characteristics of Bacillus (shape, oxygen, motility, DNA, virulence factors) correct
answers -large, encapsulated G+ rods
-aerobic spore former
-non-motile
-mesophilic
-mesopHilic
-SAME chromosomal sequence (pathovars of a single species: B. anthracis, B. cereus, B.
thuringiensis)
-PLASMIDS confer pathogenicity (there are different virulence factors in the plasmids) pXO1 &
pXO2 in B. anthracis

DISEASES: Cutaneous Anthrax (untreated, incubation period, 2 symptoms) correct answers -
Acquired by contact
-rarely fatal if treated promptly
-5-20% fatal if untreated
-2-3 days incubation

, -Symptoms
---papule (2-3 days) > pustule (7 days) > eschar (anthrakis-coal black)
---progression to septicemia (20%) shock and death

Georgics (Virgil Describing Anthrax) correct answers -anthrax is found in the soil that animals
graze
-need to bury the animals
-wear vests made of their hide= red blisters

DISEASES: Gastrointestinal Anthrax (fatality, incubation period, symptoms) correct answers -
ingesting contaminated meat
-mostly fatal (approaching 100%), even if treated bc it is often found too late
-incubation 3-5 days
-symptoms
---nausea, vomiting, diarrhea (blood may be present, lesions on intestinal wall)
---shock and death

DISEASES: Inhalation (pulmonary) anthrax
(who, fatality, incubation period, symptoms) correct answers -aka Woolsorter's Disease
-at risk: shearers, wool sorters, tanners, drum makers
-often fatal (45-80%), even if treated
-95% if treated after 48 hr infection (need treatment very early)
->99% if untreated
-1-6 days incubation
-Symptoms
---fever, malaise, myalgia, unproductive cough, no congestion
---within days, respiratory distress and cyanosis
---shock and death within 24 hours
---easy to get into blood from lungs

Sources of Infection correct answers -Soil (for animals)
-Animal Hides/Wool (cutaneous & inhalation)
-contaminated meat

Transmission correct answers -through cut/abrasions > cutaneous
-aerosols from hides, wool (not coughing): it is NOT CONTAGIOUS
-food: contaminated meat

Modus Operandi (Cutaneous Infection)
Portal of Entry, Spores correct answers -portal of entry: spores > cut
-macrophages ingest spores, spores germinate, and the bacteria multiples
-germination signal= L-alanine
-infected macrophages can spread anthrax into lymph nodes and blood

Modus Operandi (Gastrointestinal Infection)

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller FullyFocus. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $10.49. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

79650 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$10.49
  • (0)
  Add to cart