NAPLEX 2024 - 2
Demadex - ANS Torsemide
CYP inducers - ANS *PS PORCS*: phenytoin, smoking, phenobarbital, oxcarbazepine,
rifampin, carbamazepine, St. John's wort
Effect: Decrease in drug serum
CYP inhibitors - ANS *G heart PACMAN*: grapefruit, protease inhibitor (ritonavir), azole
antifungals, C (cyclosporine cimetidine), macro codes, amiodarone, non-CCB (diltiazem,
cardizem)
Effect: INcrease drug in serum
VFEND - ANS Voriconazole
G6PD deficiency - ANS - < 5 units/gram, determines hemolytic anemia (triggered by stress or
drugs: chloroquine, dapsone, methylene blue, probenecid, primaquine, quinidine, quinine,
macrobid)
CBZ therapeutic range - ANS 4-12 mcg/mL
Digoxin therapeutic range - ANS 0.8-2.0 ng/mL (AFib)
0.5-0.9 (HF)
Gentamicin therapeutic range - ANS Peak: 5-10 mcg/mL
Trough: <2 mcg/mL
Lithium therapeutic range - ANS 0.6-1.2 mEq/L (up to 1.5 mEq/L for acute symptoms)
Phenytoin therapeutic range - ANS 10-20 mcg/mL; free phenytoin 1-2.5
Procainamide therapeutic range - ANS 4-10 mcg/mL
NAPA: 15-24
Combined: 10 - 30
Theophylline therapeutic range - ANS 5-15 mcg/mL
Tobramycin therapeutic range - ANS Peak: 5-10 mcg/mL
Trough: <2 mcg/mL
,Valproic acid therapeutic range - ANS 50-100 mcg/mL
Vancomycin therapeutic range - ANS 10-20 mcg/mL
Warfarin therapeutic range - ANS INR: 2-3
Cubicin - ANS Daptomycin
ELISA - ANS enzyme-linked immunosorbent assay (test to detect anti-HIV antibodies)
TPMT - ANS those with TPMT are at increased risk of myelosuppression (bone marrow
suppression). require lower dose of azathioprine and mercaptopurine
Coombs disease - ANS - Positive = drug induced hemolysis
penicillins, cephalosporins, isoniazid, levodopa, methyldopa, nitrofurantoin, quinidine, quinine,
rifampin, sulfonamides
Hypothyroid - ANS increased TSH, decrease FT4
Hyperthyroid - ANS decrease TSH, increase FT4
INR - ANS normally <1.2, on warfarin 2-3
Half lives to steady state: - ANS 5
BiDil - ANS isosorbide dinitrate/hydralazine
*Hydralazine can cause drug induced lupus
Atacand - ANS Candesartan
Inspra - ANS Eplerenone
Dyazide - ANS Triamterene/HCTZ
Tegretol - ANS Carbamazepine
Drugs that cause low Na: - ANS Carbamazepine, oxcarbazepine, SSRIs, diuretics,
desmopressin
Trileptal - ANS oxcarbazepine
aPTT - ANS Used to monitor unfractionated heparin, the tx goal is to achieve 1.5-2 times tx
goal (22-38 seconds, so 42)
,MMA - ANS used to help determine b12 deficiency
ASHP Drug induced Diseases - ANS ADE rxns
FDAble - ANS FDA searchable database of adverse rxn
MedWatch - ANS FDA safety info and ADE reporting system (FAERS)
VAERS - ANS Vaccine Adverse Event Reporting System
USP 795 - ANS Non-sterile compounding
USP 797 - ANS Sterile preparations
USP 800 - ANS Hazardous Drugs - Handling in Healthcare Settings
USN-NF - ANS monographs for drug substances, dosage forms, compounded preparations
and excipients
Hansten and Horn's - ANS Drug interactions
Remington - ANS Compound and pharmaceutics
Red Book - ANS drug pricing
FDA's orange book - ANS approved drug products with therapeutic equivalence evaluations
FDA's purple book - ANS lists of licensed biological products with reference product exclusivity
and biosimilarity
CDC Pink book - ANS vaccine preventable disease
Sanford guide - ANS antibiotic selection and dosing
Index Nominum - ANS international drug directory
Martindale - ANS The complete drug reference
Harriet Lane Handbook - ANS Pediatrics
Diagnosis and treatment guide
King guide & Trissel's - ANS IV drug compatibility and stability
, Briggs and Hale's - ANS Pregnant and lactation
Red book (AAP) - ANS Summaries of pediatric infectious diseases, antimicrobial tx and
vaccinations
Yellow book - ANS information on the hearth risks of international travel, required vaccines and
pix medications
Green book - ANS info on approved animal products
Merck index - ANS compound and pharmaceuticals
Merck manual - ANS General disease categories and their treatments
Natural Medicines Comprehensive Database - ANS Includes entries for many natural, herbal,
alternative medicines listed alphabetically
Pink sheet - ANS Biopharma regulatory, legislative, legal and business developments
Drugs with issues to PVC containers: - ANS LATTIN
Lorazepam
Amiodarone
Tacrolimus
Taxanes
Insulin
Nitroglycerin
(other random: sufentanil, carmustine, ixabepilone, temsirolimus, teniposide, thiopental)
Mix with only saline - ANS *ACID APE dips his bananas in salt*
Ampicillin
Caspofungin (Cancidas)
Infliximab (Remicade)
Daptomycin (cubicin)
Ampicillin/Sulbactam (Unasyn)
Phenytoin
Ertapenemen (Invanz)
Mix with only dextrose - ANS *BOAS will strangle pharmacist who mix with salt*
Bacterium
Oxaliplatin
Demadex - ANS Torsemide
CYP inducers - ANS *PS PORCS*: phenytoin, smoking, phenobarbital, oxcarbazepine,
rifampin, carbamazepine, St. John's wort
Effect: Decrease in drug serum
CYP inhibitors - ANS *G heart PACMAN*: grapefruit, protease inhibitor (ritonavir), azole
antifungals, C (cyclosporine cimetidine), macro codes, amiodarone, non-CCB (diltiazem,
cardizem)
Effect: INcrease drug in serum
VFEND - ANS Voriconazole
G6PD deficiency - ANS - < 5 units/gram, determines hemolytic anemia (triggered by stress or
drugs: chloroquine, dapsone, methylene blue, probenecid, primaquine, quinidine, quinine,
macrobid)
CBZ therapeutic range - ANS 4-12 mcg/mL
Digoxin therapeutic range - ANS 0.8-2.0 ng/mL (AFib)
0.5-0.9 (HF)
Gentamicin therapeutic range - ANS Peak: 5-10 mcg/mL
Trough: <2 mcg/mL
Lithium therapeutic range - ANS 0.6-1.2 mEq/L (up to 1.5 mEq/L for acute symptoms)
Phenytoin therapeutic range - ANS 10-20 mcg/mL; free phenytoin 1-2.5
Procainamide therapeutic range - ANS 4-10 mcg/mL
NAPA: 15-24
Combined: 10 - 30
Theophylline therapeutic range - ANS 5-15 mcg/mL
Tobramycin therapeutic range - ANS Peak: 5-10 mcg/mL
Trough: <2 mcg/mL
,Valproic acid therapeutic range - ANS 50-100 mcg/mL
Vancomycin therapeutic range - ANS 10-20 mcg/mL
Warfarin therapeutic range - ANS INR: 2-3
Cubicin - ANS Daptomycin
ELISA - ANS enzyme-linked immunosorbent assay (test to detect anti-HIV antibodies)
TPMT - ANS those with TPMT are at increased risk of myelosuppression (bone marrow
suppression). require lower dose of azathioprine and mercaptopurine
Coombs disease - ANS - Positive = drug induced hemolysis
penicillins, cephalosporins, isoniazid, levodopa, methyldopa, nitrofurantoin, quinidine, quinine,
rifampin, sulfonamides
Hypothyroid - ANS increased TSH, decrease FT4
Hyperthyroid - ANS decrease TSH, increase FT4
INR - ANS normally <1.2, on warfarin 2-3
Half lives to steady state: - ANS 5
BiDil - ANS isosorbide dinitrate/hydralazine
*Hydralazine can cause drug induced lupus
Atacand - ANS Candesartan
Inspra - ANS Eplerenone
Dyazide - ANS Triamterene/HCTZ
Tegretol - ANS Carbamazepine
Drugs that cause low Na: - ANS Carbamazepine, oxcarbazepine, SSRIs, diuretics,
desmopressin
Trileptal - ANS oxcarbazepine
aPTT - ANS Used to monitor unfractionated heparin, the tx goal is to achieve 1.5-2 times tx
goal (22-38 seconds, so 42)
,MMA - ANS used to help determine b12 deficiency
ASHP Drug induced Diseases - ANS ADE rxns
FDAble - ANS FDA searchable database of adverse rxn
MedWatch - ANS FDA safety info and ADE reporting system (FAERS)
VAERS - ANS Vaccine Adverse Event Reporting System
USP 795 - ANS Non-sterile compounding
USP 797 - ANS Sterile preparations
USP 800 - ANS Hazardous Drugs - Handling in Healthcare Settings
USN-NF - ANS monographs for drug substances, dosage forms, compounded preparations
and excipients
Hansten and Horn's - ANS Drug interactions
Remington - ANS Compound and pharmaceutics
Red Book - ANS drug pricing
FDA's orange book - ANS approved drug products with therapeutic equivalence evaluations
FDA's purple book - ANS lists of licensed biological products with reference product exclusivity
and biosimilarity
CDC Pink book - ANS vaccine preventable disease
Sanford guide - ANS antibiotic selection and dosing
Index Nominum - ANS international drug directory
Martindale - ANS The complete drug reference
Harriet Lane Handbook - ANS Pediatrics
Diagnosis and treatment guide
King guide & Trissel's - ANS IV drug compatibility and stability
, Briggs and Hale's - ANS Pregnant and lactation
Red book (AAP) - ANS Summaries of pediatric infectious diseases, antimicrobial tx and
vaccinations
Yellow book - ANS information on the hearth risks of international travel, required vaccines and
pix medications
Green book - ANS info on approved animal products
Merck index - ANS compound and pharmaceuticals
Merck manual - ANS General disease categories and their treatments
Natural Medicines Comprehensive Database - ANS Includes entries for many natural, herbal,
alternative medicines listed alphabetically
Pink sheet - ANS Biopharma regulatory, legislative, legal and business developments
Drugs with issues to PVC containers: - ANS LATTIN
Lorazepam
Amiodarone
Tacrolimus
Taxanes
Insulin
Nitroglycerin
(other random: sufentanil, carmustine, ixabepilone, temsirolimus, teniposide, thiopental)
Mix with only saline - ANS *ACID APE dips his bananas in salt*
Ampicillin
Caspofungin (Cancidas)
Infliximab (Remicade)
Daptomycin (cubicin)
Ampicillin/Sulbactam (Unasyn)
Phenytoin
Ertapenemen (Invanz)
Mix with only dextrose - ANS *BOAS will strangle pharmacist who mix with salt*
Bacterium
Oxaliplatin
