CCTC Study Guide Questions with All Correct Answers
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CCTC
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CCTC
CCTC Study Guide Questions with All Correct Answers
What types of cells are considered APC's - Answer- Dendritic Cells, Monocytes and Macrophages
APC's are known as scavengers-why? - Answer- they engulf debris of dead cells especially in apoptotic cell death
which cells engulf foreign c...
CCTC Study Guide Questions with
All Correct Answers
What types of cells are considered APC's - Answer- Dendritic Cells, Monocytes and
Macrophages
APC's are known as scavengers-why? - Answer- they engulf debris of dead cells
especially in apoptotic cell death
which cells engulf foreign cells and express them on cell surface? - Answer-
macrophages
What activates APC's - Answer- if they eat a foreign antigen
Direct Pathway for APC always comes from the:
a. donor
b. recipient - Answer- A. Donor
Donor APC's are also known as - Answer- Passenger Leukocytes (along for the ride
with the donor organ)
Indirect Pathway for APC always comes from the:
a. recipient
b. donor - Answer- A. Recipient
How do Recipient APC's function - Answer- they can absorb and present foreign donor
antigens and present them to CD4 T helper cells
which cells are key to recognizing foreign proteins - Answer- Lymphocytes
How do lymphocytes function - Answer- they mount a response to foreign antigens
name the 3 t-cell sub-groups based - Answer- Helper = CD4
Cytotoxic = CD8
B Lymphocytes
t helper cells - CD4 - Answer- directly communicate with other cells and communicate
via cytokines
what are the two types of t helper cells - Answer- t helper 1 (with cellular response)
, t helper 2 ( with humoral response)
t helper 1's bind with... - Answer- class two antigens
what order does the cellular response happen - Answer- t helper 1's bind, release IL2,
stimulates effector t-cells (aka CD8) or macrophage, once activated they attack donor
cells
what is the mechanism of the humoral response - Answer- t helper 2 secretes IL4, Il5,
Il6
what stimulates the proliferation of B lymphocytes - Answer- the secretion of IL4-IL6
B lymphocytes turn into what - Answer- plasma cells
Plasma cells produce what? - Answer- antibodies
Cytotoxic T cells are otherwise known as - Answer- CD8 cells
what are CD8 cells activated by - Answer- IL2 release
How do CD8 cells kill target cells - Answer- adhering to foreign antigens associated with
class 1 molecules
name a co receptor molecule on a cell membrane - Answer- CD8 cell
Where are B lymphocytes made? - Answer- bone marrow
3 a's in cellular immunity - Answer- antigen cells (macrophages), Alert helper T cells
that a foreign (non self) entity is present, Activate mechanism to destroy non self cells
what mechanism activates cellular immunity - Answer- determined by reticuloendothelial
system
Name the three Immune System Protection Mechanisms - Answer- surveillance,
defense and homeostasis
Surveillance - Answer- recognize antigens (foreign) on cell membranes and
microorganisms
Defence - Answer- destruction of foreign entities and specific targeting thru Humoral or
Cellular Mechanism
Homeostasis - Answer- Balance protection and destruction
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