NURS 3550 Test 2 Review questions with correct
answers
Effects of Morphine at Mu Receptors Correct Answer-analgesia
sedation
euphoria*
physical dependence*
respiratory depression*
miosis (pinpoint)*
vasodilation*
decreased GI activity
Effects of Morphine at Kappa Receptors Correct Answer-Analgesia
Sedation
Hallucinations*
Dysphoria*
Nightmares*
Decreased GI activity
What type of drug is pentazocine? Correct Answer-A mixed opioid
agonist-antagonist that mostly activates kappa receptors and blocks mu
receptors
What type of drug is morphine? Correct Answer-Opioid agonist
,Why use pentazocine over a pure opioid agonist? Correct Answer-Better
choice in someone who has an issue with euphoria, respiratory
depression, or dependence
May not be a good choice in someone with problems with dysphoria or
high BP
What enzyme(s) metabolize morphine? Correct Answer-CYP 2D6 and
CYP 3A4
Therapeutic Indication of Morphine Correct Answer-1. Treatment of
moderate to severe pain by decreasing transmission pain (Substance P)
2. Diarrhea (by decreasing GI motility - Loperamide)
3. Cough suppression (codeine)
Contraindications of Morphine Correct Answer-1.
Hypersensitivity/Allergy
2. Premature Neonates
3. Heart Failure from lung disease
4. Arrhythmia
5. Biliary Tract Surgery
Cautions of Morphine Correct Answer-1. Compromised respiratory
function
2. Head injury
3. Pregnancy
,4. Labour and Delivery
5. Infants/Elderly
6. IBD
7. Hepatic dysfunction
8. Hypotension/hypovolemia
9. BPH
10. Hx of drug dependence
How much of dose of morphine actually reach the site of action and
why? Correct Answer-- only a fraction
- not very lipid soluble, does not cross BBB very easily
What are some effects of prolonged use of morphine? Correct Answer--
Compromised immune system
- Neurotoxicity
- Decreased cortisol
- Increased prolactin
- Decreased LH, FSH, testosterone and estrogen
What is the classic triad of overdose/toxicity? Correct Answer--
Respiratory depression
- Miosis
- Coma
, What are some symptoms of opioid withdrawal? Correct Answer--
yawning
- sweating
- sneezing
- muscle and bone pain
- muscle spasm and kicking
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller cracker. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $15.49. You're not tied to anything after your purchase.