Class notes
Covid-19 and Microbiology
- Course
- Bio 250 (BIO250)
- Institution
- University Of South Carolina
This is a brief review of Covid-19 and the biology behind the disease.
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CoronaVirusFirst IDed as animal diseases in the 1930’s
Dr.June Almeida: first human CoV
- research waned (difficult to culture)
- Finding cures were hard
Interest faded
Round 1: SARS
Outbreak of SARS in Guangdong, thought to be pneumonia
- Jan. 2003: super-spreader infects 30 nurses and doctors
- Feb. 2003: virus spread to Hong Kong, Vietnam, and Canada (China finally identifies
305 cases)
- March. 2003: Spreads to Singapore, Taiwan, air travelers are now isolated
- Continues to spread across globe by May
Suspected Cases as of May 6, 2003: 320 from U.S.
China had 349 dead: 6.6% mortality rate
U.S: 27 cases definitively confirmed: 0 deaths
Came through horseshoe bats and passed through Asian palm civets before infecting humans
Crown virus: spike proteins make it look crown-like
- novel (not before known) human CoV viruses
- NL63: been around since 1981
2016: MERS (Middle eastern respiratory syndrome)
- host were camels, originally also came from bats
1700 cases and about 680 deaths: 39.1% mortality
- still have some sporadic cases
SARS however, did go away: haven’’t seen it until this year, a different one
Dr. Xiang geo Qiu alleged Chinese biological warfare agent, who sent fatal disease samples to
Wuhan: some reports say Covid strain was included
SARS-CoV-2: Official Timeline
Oct-Nov: 2019: Thought to have spread via the seafood market
BUT
COVID-like cases came up in September
Dec 1.: patient 0
- 70 year old man in Wuhan had no contact with the wet market (freshly slaughtered
animals)
Dec. 16: first hospitalization for mystery pneumonia
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