Campylobacter &
Helicobacter
General Characteristics
Common to Superfamily
Gram-negative
Helical (spiral or curved) morphology; Tend to be
pleomorphic
Characteristics that facilitate penetration and
colonization of mucosal environments (e.g.,
motile by polar fl...
, General Characteristics
Common to Superfamily
Gram-negative
Helical (spiral or curved) morphology; Tend to be
pleomorphic
Characteristics that facilitate penetration and
colonization of mucosal environments (e.g.,
motile by polar flagella; corkscrew shape)
Microaerophilic atmospheric requirements
Become coccoid when exposed to oxygen or
upon prolonged culture
Neither ferment nor oxidize carbohydrates
, History of Campylobacter
First isolated as Vibrio fetus in 1909 from
spontaneous abortions in livestock
Campylobacter enteritis was not recognized
until the mid-1970s when selective isolation
media were developed for culturing
campylobacters from human feces
Most common form of acute infectious
diarrhea in developed countries; Higher
incidence than Salmonella & Shigella combined
In the U.S., >2 million cases annually, an annual
incidence close to the 1.1% observed in the
United Kingdom; Estimated 200-700 deaths
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