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NR 507 midterm 2024 LATEST UPDATE CORRECT 100%

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Hives (urticaria) are an example of a: - ANSWER Type 1 hypersensitivity reaction. Anaphylaxis is what type of reaction? - ANSWER type 1 hypersensitivity Which of the following are considered the "first responders" of the innate immune system? - ANSWER neutrophils Allergic contact dermatitis is an example of what type of hypersensitivity reaction. - ANSWER type 4 hypersensitivity reaction

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NR 507 ADVANCED PATHOPHYSIOLOGY
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NR 507 ADVANCED PATHOPHYSIOLOGY

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NR 507 midterm 2024 LATEST UPDATE
CORRECT 100%

Hives (urticaria) are an example of a: - ANSWER Type 1 hypersensitivity reaction.



Anaphylaxis is what type of reaction? - ANSWER type 1 hypersensitivity



Which of the following are considered the "first responders" of the innate immune system? - ANSWER
neutrophils



Allergic contact dermatitis is an example of what type of

hypersensitivity reaction. - ANSWER type 4 hypersensitivity reaction



Type 2 (Cytotoxic) hypersensitivity reactions are mediated by: - ANSWER IgG or IgM



Type 1 hypersensitivity reaction is mediated by - ANSWER IgE



Allergic asthma is an example of - ANSWER type 1 hypersensitivity reaction



type 2 hypersensitivity - ANSWER tissue specific



Primary effector cells of type 2 - ANSWER macrophages



Examples of type 2 reactions - ANSWER drug allergies, hemolytic anemia, blood transfusion mismatch,
allergies against infectious agents



Type 2 causes - ANSWER The cell to be destroyed by the antibody

Cell destruction through phagocytosis by macrophages

, Damage to the cell by neutrophils triggering phagocytosis

Natural killer cells to release toxic substances that destroy the target cell

Malfunction of the cell without destruction



Type 3 hypersensitivity reaction - ANSWER antigen-antibody response



Where does the antibody bind to the antigen in type 3 response? - ANSWER in blood or body fluids and
then circulates to tissue



Where does the antibody bind to the antigen in type 1, 2, and 4? - ANSWER on cell surface



Primary effector cell in type 3 - ANSWER neutrophils



example of type 3 reaction - ANSWER serum sickness



type 4 hypersensitivity reaction - ANSWER cell-mediated response



primary mediators of type 4 - ANSWER lymphocytes and macrophages



type 4 mediated by - ANSWER T lymphocytes and do not use antibodies



example of type 4 - ANSWER localized contact dermatitis (poison ivy)



Damage occurs with ABO incompatibility because: - ANSWER Complement damages RBC membrane
causing cell lysis.



Which of the following is the underlying pathology for hay fever? - ANSWER mast cell degranulation



The diagnosis for an individual who presents to the office with sudden swollen lips and eyes, shortness
of breath and throat tightness after a bee sting is: - ANSWER anaphylaxis

, Which of the following assessment findings would be expected in a patient who presents with urticaria?
- ANSWER Eosinophilia.



An example of a primary immunodeficiency is: - ANSWER Chronic Granulomatous Disease.



what is a predominant cause of secondary immune deficiencies worldwide. - ANSWER Malnutrition



Which of the following is an autoimmune disease? - ANSWER Systemic Lupus Erythematosus (SLE).



Which is true about a primary immunodeficiency? - ANSWER It is the result of a single gene defect.
(genetics)



Examples of secondary immunodeficiency - ANSWER HIV, cancer



Secondary immunodeficiency caused by - ANSWER external to immune system



examples of primary immunodeficiency - ANSWER Chronic granulomatous Disease of Childhood

DiGeorge Syndrome

Familial Mediterranean fever

Job Syndrome

Common Variable Immunodeficiency



examples of secondary immunodeficiency - ANSWER Human Immunodeficiency Virus

Pneumocystis Carinii

Pneumonia

Sinus infection

Lung cancer

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NR 507 ADVANCED PATHOPHYSIOLOGY
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NR 507 ADVANCED PATHOPHYSIOLOGY

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