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Test Bankfor Pharmacotherapeutics for AdvancedPractice A
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Practical Approach 5th Edition By Virginia Poole Arcangelo,
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Andrew M Peterson, Veronica Wilbur, Tep M. Kang/ All
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Chapters Covered – Latest Update 2024. v v v v v
Nurse practitioner prescriptive authority is regulated by:
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1. The National Council of State Boards of Nursing
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2. The U.S. Drug Enforcement Administration
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3. The State Board of Nursing for each state
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4. The State Board of Pharmacy - Correct Answer - 3. The State Board of Nursing for each state
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The benefits to the patient of having an Advanced Practice Registered Nurse (APRN) prescriber include:
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1. Nurses know more about Pharmacology than other prescribers because they take it both in their basic
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nursing program and in their APRN program.
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2. Nurses care for the patient from a holistic approach and include the patient in decision making
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regarding their care.
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3. APRNs are less likely to prescribe narcotics and other controlled substances.
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4. APRNs are able to prescribe independently in all states, whereas a physician's assistant needs to have a
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physician supervising their practice. - Correct Answer - 2. Nurses care for the patient from a holistic
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approach and include the patient in decision making regarding their care.
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Clinical judgment in prescribing includes:
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1. Factoring in the cost to the patient of the medication prescribed
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2. Always prescribing the newest medication available for the disease process
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3. Handing out drug samples to poor patients v v v v v v
4. Prescribing all generic medications to cut costs - Correct Answer - 1. Factoring in the cost to the
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patient of the medication prescribed
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pg. 1
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,Criteria for choosing an effective drug for a disorder include:
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1. Asking the patient what drug they think would work best for them
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2. Consulting nationally recognized guidelines for disease managementv v v v v v
3. Prescribing medications that are available as samples before writing a prescription
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4. Following U.S. Drug Enforcement Administration guidelines for prescribing - Correct Answer - 2.
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Consulting nationally recognized guidelines for disease management
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Nurse practitioner practice may thrive under health-care reform because of:
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1. The demonstrated ability of nurse practitioners to control costs and improve patient outcomes
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2. The fact that nurse practitioners will be able to practice independently
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3. The fact that nurse practitioners will have full reimbursement under health-care reform
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4. The ability to shift accountability for Medicaid to the state level - Correct Answer - 1. The
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demonstrated ability of nurse practitioners to control costs and improve patient outcomes
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A patient's nutritional intake and laboratory results reflect hypoalbuminemia. This is
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critical to prescribing because:
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1. Distribution of drugs to target tissue may be affected. v v v v v v v v
2. The solubility of the drug will not match the site of absorption.
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3. There will be less free drug available to generate an effect.
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4. Drugs bound to albumin are readily excreted by the kidneys. - Correct Answer - 1. Distribution of drugs to
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target tissue may be affected.
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Drugs that have a significant first-pass effect:
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1. Must be given by the enteral (oral) route only
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2. Bypass the hepatic circulation v v v
3. Are rapidly metabolized by the liver and may have little if any desired action
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pg. 2v
,4. Are converted by the liver to more active and fat-soluble forms - Correct Answer - 3. Are rapidly
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metabolized by the liver and may have little if any desired action
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The route of excretion of a volatile drug will likely be the:
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1. Kidneys
2. Lungs
3. Bile and feces v v
4. Skin - Correct Answer - 2. Lungs
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Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create a storage reservoir of v v v v v v v v v v v v
the drug. Storage reservoirs:
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1. Assure that the drug will reach its intended target tissue
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2. Are the reason for giving loading doses
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3. Increase the length of time a drug is available and active
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4. Are most common in collagen tissues - Correct Answer - 3. Increase the length of time a drug is
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available and active
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The NP chooses to give cephalexin every 8 hours based on knowledge of the drug's:
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1. Propensity to go to the target receptor v v v v v v
2. Biological half-life v
3. Pharmacodynamics
4. Safety and side effects - Correct Answer - 2. Biological half-life
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Azithromycin dosing requires that the first day's dosage be twice those of the other 4 days of the
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prescription. This is considered a loading dose. A loading dose:
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1. Rapidly achieves drug levels in the therapeutic range
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2. Requires four- to five-half-lives to attain v v v v v
3. Is influenced by renal function
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4. Is directly related to the drug circulating to the target tissues - Correct Answer - 1. Rapidly achieves
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drug levels in the therapeutic range
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pg. 3
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, The point in time on the drug concentration curve that indicates the first sign of a therapeutic effect is the:
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1. Minimum adverse effect level v v v
2. Peak of action v v
3. Onset of action v v
4. Therapeutic range - Correct Answer - 3. Onset of action v v v v v v v v v
Phenytoin requires that a trough level be drawn. Peak and trough levels are done:
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1. When the drug has a wide therapeutic range
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2. When the drug will be administered for a short time only
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3. When there is a high correlation between the dose and saturation of receptor sites
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4. To determine if a drug is in the therapeutic range - Correct Answer - 4. To determine if a drug is in the
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therapeutic range
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A laboratory result indicates that the peak level for a drug is above the minimum toxic concentration. This
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means that the:
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1. Concentration will produce therapeutic effects v v v v
2. Concentration will produce an adverse response v v v v v
3. Time between doses must be shortened
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4. Duration of action of the drug is too long - Correct Answer - 2. Concentration will produce an adverse
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response
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Drugs that are receptor agonists may demonstrate what property?
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1. Irreversible binding to the drug receptor site v v v v v v
2. Upregulation with chronic use v v v
3. Desensitization or downregulation with continuous use v v v v v
4. Inverse relationship between drug concentration and drug action - Correct Answer - 3. Desensitization or
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downregulation with continuous use
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pg. 4v
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