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INBDE Pharmacology Exam Questions with 100% Correct Answers 2024/2025 Latest Update

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INBDE Pharmacology Exam Questions with 100% Correct Answers 2024/2025 Latest Update Which of the following antibiotics may be cross-allergenic with penicillin? a. neomycin b. cephalexin c. erythromycin d. clindamycin e. all of the above - Answer- b. cephalexin Use of prilocaine carrie...

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  • November 21, 2024
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  • 2024/2025
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INBDE Pharmacology Exam Questions
with 100% Correct Answers 2024/2025
Latest Update

Which of the following antibiotics may be cross-allergenic with penicillin?
a. neomycin
b. cephalexin
c. erythromycin
d. clindamycin
e. all of the above - Answer- b. cephalexin

Use of prilocaine carries the risk of which of the following adverse effects?
a. porphyria
b. renal toxicity
c. gastric bleeding
d. methemoglobinemia - Answer- d. methemoglobinemia

Quinidine is principally used to treat
a. hypertension
b. angina pectoris
c. congestive heart failure
d. supraventricular tachyarrhythmia - Answer- d. supraventricular tachyarrhythmia

An analgesic compound #3 contains how many mg of codeine?
a. 7.5
b. 15
c. 30
d. 60 - Answer- c. 30

Thiazides, which are used in the treatment of hypertension, may require supplemental
administration of
a. sodium
b. chloride
c. calcium
d. potassium - Answer- d. potassium
-Thiazide diuretics can cause low K+ (hypokalemia)

Which of the following is an example of an enteral route of administration?
a. oral
b. submucosal

,c. inhalation
d. subcutaneous
e. intramuscular - Answer- a. oral
-enteral= gastrointestinal route
-subenteral= sublingual, subcutaneous, IM, IV, inhalation, topical

Neostigmine produces its effect by
a. depressing acetylcholinesterase release
b. inhibiting acetylcholinesterase activity
c. increasing the rate of acetylcholine synthesis
d. acting like acetylcholine at ganglionic sites
e. increasing the amount of acetylcholine released from nerve terminals - Answer- b.
inhibiting acetylcholinesterase activity

Tetracycline reduces the effectiveness of concomitantly administered penicillin by
a. reducing absorption of penicillin
b. increasing metabolism of penicillin
c. increasing renal excretion of penicillin
d. increasing binding of penicillin to serum proteins
e. none of the above - Answer- e. none of the above
-Tetracycline= bacteriostatic= slows growth
-Penicillin= bacteriostatic= kills bacteria

You are performing a root canal treatment on a patient who suffers from dental anxiety.
You decide to prescribe Valium pre-operatively. Benzodiazepines produce their anti-
anxiety effects by modulating which of the following neurohumors?
a. GABA
b. glycine
c. dopamine
d. acetylcholine
e. norepinephrine - Answer- a. GABA

You check the medical history for this same patient and notice he is taking Aspirin. Anti-
inflammatory agents, such as aspirin, interfere
with hemostasis by
A. Activating antithrombin
B. Preventing vasoconstriction
C. Inhibiting thrombin generation
D. Inhibiting platelet aggregation
E. Inhibiting polymerization of fibrin - Answer- D. Inhibiting platelet aggregation
-inhibits thromboxane A2


Amides are metabolized by - Answer- liver

Esters are metabolized by - Answer- pseudocholinesterase in plasma

, Local anesthesia: Amides - Answer- have 2 or more "i" in the name
-Lidocaine (2%)
-Bupivicaine (0.5%)
-Articaine (4%) (Septocaine)
-Mepivicaine (2% & 3%) (Carbocaine)
-Prilocaine

which local anesthetic is safest in children? - Answer- Lidocaine

which local anesthetic is NOT safe in children and has the longest duration? - Answer-
Bupivicaine

which local anesthetic causes the least vasodilation and can be packaged without a
vasoconstrictor? - Answer- Mepivicaine (Carbocaine)

which local anesthetic has one ester, is metabolized by both the liver and blood plasma,
and has the shortest duration of action? - Answer- Articaine (Septocaine)

which local anesthetic can cause methemoglobinemia and is contraindicated in patients
with hepatic (liver) disease? - Answer- Prilocaine

Local anesthesia: Esters - Answer- have 1 "i" in the name
-Procaine
-Cocaine
-Tetracaine
-Benzocaine

which local anesthetic causes vasoconstriction? - Answer- Cocaine

Pharmacodynamics = - Answer- what the drug does to the body

Pharmacodynamics:
Local anesthetics are - Answer- sodium channel blockers
-only non-ionized (uncharged/free base) form can penetrate neuron membrane

Pharmacokinetics = - Answer- what the body does to the drug

increased blood flow to the site = - Answer- shorter duration of action

increased lipid solubility/hydrophobicity = - Answer- more potent; longer duration of
action
-more drug can diffuse through the membrane

increased protein binding = - Answer- longer duration of action
-anesthetic has greater attraction to the receptor sites

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