MCB5205 TEST WITH COMPLETE
SOLUTION
Thymus - ANSWER where T cells mature
lymphatic system - ANSWER way in which the immune cells travel through
the body between blood and other sites
bone marrow - ANSWER where B cells mature
where stem cells originate
granulocyte - ANSWER neutrophils
basophils
eosinophils
contain cytotoxic granules
dendritic cells - ANSWER -APC
-phagocyte that can degrade pathgogens
-primary role is activation of B/T cells
- localized and are special for certain tissues
innate immune cells (6) - ANSWER granulocytes
DC's
macrophages
neutrophils
,mast cells
NK cells
innate immunity characteristics (4) - ANSWER always on
rapid response
non-specific
short duration
adaptive immunity characteristics - ANSWER Memory
Slower response
specific
neutrophils - ANSWER PMN's
- phagocytic
- found in blood
- undergo apoptosis after phagocytosis
- most common type
- short lifespan
is a neutrophil an APC? - ANSWER NO (but it is a phagocyte)
Macrophage - ANSWER - phagocytic
- process and present Ag
- activate B/T cells
- produce cytokines and chemokines
, what is the immature form of a macrophage - ANSWER monocyte
is a dendritic cell an APC? - ANSWER YES
what is the bridge between innate and adaptive immunity - ANSWER
Dendritic Cells
Mast cell - ANSWER - non phagocytic
- releases histamine
- involved in inflammation
NK cells - ANSWER - non phagocytic
- provide protection against intracellular pathogens
- primary producer of IFN-y
- can lyse tumor cells
what cell is the primary producer of IFN-y - ANSWER NK cells
TLR - ANSWER exposed on surface of phagocytes and have a critical role in
initiating the innate immune response
- PRR's recognize PAMP's
MCH-1 - ANSWER - presents Ag from INTRACELLULAR/VIRAL pathogens
- interacts w/ CD8T cells
MHC-II - ANSWER - presents Ag from EXTRACELLULAR pathogens
SOLUTION
Thymus - ANSWER where T cells mature
lymphatic system - ANSWER way in which the immune cells travel through
the body between blood and other sites
bone marrow - ANSWER where B cells mature
where stem cells originate
granulocyte - ANSWER neutrophils
basophils
eosinophils
contain cytotoxic granules
dendritic cells - ANSWER -APC
-phagocyte that can degrade pathgogens
-primary role is activation of B/T cells
- localized and are special for certain tissues
innate immune cells (6) - ANSWER granulocytes
DC's
macrophages
neutrophils
,mast cells
NK cells
innate immunity characteristics (4) - ANSWER always on
rapid response
non-specific
short duration
adaptive immunity characteristics - ANSWER Memory
Slower response
specific
neutrophils - ANSWER PMN's
- phagocytic
- found in blood
- undergo apoptosis after phagocytosis
- most common type
- short lifespan
is a neutrophil an APC? - ANSWER NO (but it is a phagocyte)
Macrophage - ANSWER - phagocytic
- process and present Ag
- activate B/T cells
- produce cytokines and chemokines
, what is the immature form of a macrophage - ANSWER monocyte
is a dendritic cell an APC? - ANSWER YES
what is the bridge between innate and adaptive immunity - ANSWER
Dendritic Cells
Mast cell - ANSWER - non phagocytic
- releases histamine
- involved in inflammation
NK cells - ANSWER - non phagocytic
- provide protection against intracellular pathogens
- primary producer of IFN-y
- can lyse tumor cells
what cell is the primary producer of IFN-y - ANSWER NK cells
TLR - ANSWER exposed on surface of phagocytes and have a critical role in
initiating the innate immune response
- PRR's recognize PAMP's
MCH-1 - ANSWER - presents Ag from INTRACELLULAR/VIRAL pathogens
- interacts w/ CD8T cells
MHC-II - ANSWER - presents Ag from EXTRACELLULAR pathogens
