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Immunology and Serology (Review) questions with verified answers

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  • Course
  • Immunology and Serology
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  • Immunology And Serology

Humoral adaptive immunity Ans-type of adaptive immunity involving B cells and antibodies Cellular adaptive immunity Ans-type of adaptive immunity involving T cells and lymphokines IgG Ans-Class of immunoglobulin with the greatest concentration in serum (75%) Antibody class capable of crossin...

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  • February 1, 2025
  • 13
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • Immunology and Serology
  • Immunology and Serology
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Immunology and Serology (Review) questions with
verified answers
Humoral adaptive immunity Ans✓✓-type of adaptive immunity involving B cells
and antibodies


Cellular adaptive immunity Ans✓✓-type of adaptive immunity involving T cells
and lymphokines


IgG Ans✓✓-Class of immunoglobulin with the greatest concentration in serum
(75%)
Antibody class capable of crossing the placenta


IgM Ans✓✓-Largest antibody (pentamer), fixes complement best
Antibody class associated with early/primary immune response


IgA Ans✓✓-predominant antibody in body secretions


IgE Ans✓✓-antibody class associated with allergies; triggers release of histamine
from mass cells


T cells Ans✓✓-Develop in thymus
Comprise 60-80% of circulating lymphs
CD2+ CD3+


T helper cells Ans✓✓-CD4+

, T suppressor cells and T cytotoxic cells Ans✓✓-CD8+


B cells Ans✓✓-Develop in bone marrow
Comprise 10-20% of circulating lymphs
CD19+ CD20+


Natural killer cells Ans✓✓-CD16+ CD56+


hybridoma Ans✓✓-cell created by the fusion of myeloma (cancerous) cells with
plasma cells to produce monoclonal antibodies


classical pathway Ans✓✓-type of complement cascade activated by IgG or IgM
immune complexes


alternative pathway Ans✓✓-type of complement cascade activated by LPS or
polysaccharide capsules


Mg2+ and Ca2+ Ans✓✓-ions required in the complement cascade


Type 1 Ans✓✓-anaphylactive, immediate hypersensitivity rxn associated with IgE
and mast cells


Type 1 hypersensitivity Ans✓✓-hypersensitivity rxn: bee sting, hay fever, asthma


Type 2 Ans✓✓-antibody dependent cytotoxity hypersentsitivity rxn

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