NURS 615 (NURS615)

1. What is Tiotropium (SPIRIVA) used to treat? - Used in the management/ maintenance treatment of chronic obstructive pulmonary disease (COPD) which includes chronic bronchitis and emphysema. 2. What is the drug classification of Tiotropium? – >It is a long-acting, 24H anticholinergic-bronchodilator. >It is a muscurinic receptor antagonist, often referred to as an antimuscurinic or anticholinergic agent. 3. What is the mechanism of action of Tiotropium (SPIRIVA) - It does not di...

1. How does hypoalbuminemia affect the process of prescribing? - Low albumin = more free drug (bc the drug can't bind to albumin aka protein) = increased adverse effects 2. What is a Black Box Warning: - is considered a contraindication to administer that drug. 3. What is the drugs half-life? - Half-life specifically means the amount of time it takes for an administered drug to be halfway cleared from the system. 4. Peak of action: - the time between drug administration and maximum co...

1. Carbamazepine (Tegretol) can sometimes show subtherapeutic range due to what? - Carbamazepine auto-induces metabolism, leading to lower levels despite good compliance 2. What are the black box warnings for Carbamazepine? - Dermatologic reactions 1. Steven's Johnson 2. Toxic epidermal necrolysis 3. What lab test should be ordered for patients on Carbamazepine? - CBC every 3-4 months because it can cause decreased WBC, decreased platelets, and trouble with RBC 4. What kind of teac...

How do antigout medications work? - by inhibiting the infiltration and phagocytosis of leukocytes, thus decreasing the breakdown of uric acid to urate crystals. Deposition of urate crystals causes - pain and inflammation What is Colchicine - anti-gout medication how does Colchicine work? - Works by inhibiting inflammation, reducing pain and swelling common side effects of Colchicine - GI problems (diarrhea) use with caution in elderly Also can cause blood dyscrasias & abdominal pain pa...

Low-dose colchine - 1.2 mg at first sign of flare, followed by 0.6 mg one hour later for a total dose of 1.8 mg. High-dose colchine - 1.2 mg followed by 0.6 mg every 4-6 hours totaling 4.8 mg. Gout - BUN, creatinine, and creatinine clearance should be monitored in the treatment of this disease Colchine - This medication can cause severe diarrhea, nausea, vomiting, abdominal pain Febuxostat (Uloric) - When prescribing this medication, patients should be taught that gout may worsen with th...

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