PCEUT

University of Washington

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PCEUT (Department of Pharmaceutics ) Bundle Set
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PCEUT (Department of Pharmaceutics ) Bundle Set

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PCEUT questions with correct answers
Exam (elaborations) • 17 pages • 2023
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oral bioavialability (F) - Answer the fraction of an orally administered dose of drug that reaches systemic circulation unchanged F = (bioavailable dose)/(oral dose) describes the extent to which a drug is absorbed from GI tract into systemic circulation factors decreasing oral bioavailability - Answer GI tract: - drug solubility - permeability across gut wall - interaction w/ gut metabolic enzymes and transporters Liver: - first pass effect What pharmacokinetic quantity ...