GMS 6504 Study guides, Class notes & Summaries
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![GMS 6504 MODULE 1-3 Exam 1 Questions and Answers 100% Correct!](/docpics/4597921/65db55471760a_4597921_121_171.jpeg)
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GMS 6504 MODULE 1-3 Exam 1 Questions and Answers 100% Correct!
- Exam (elaborations) • 7 pages • 2024
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What are System Independent Parameters? - ANSWER-Affinity 
Efficacy 
 
What are the parts of a system that are identified as System Dependent Parameters? - ANSWER-Number of receptors 
Cellular machinery 
Presence of other drugs 
- Competitive 
- Noncompetitive 
 
Affinity is - ANSWER-Thermokinetic propensity of drug to bind to receptor 
 
Based largely on ΔG 
 
Efficacy is - ANSWER-Magnitude of change of receptor shape/function upon drug binding 
 
Based on atom/atom interactions 
 
What i...
![GMS 6504 MODULE 1-3 Exam 1 Questions and Answers 100% Pass](/docpics/5295219/66431c2d54eeb_5295219_121_171.jpeg)
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GMS 6504 MODULE 1-3 Exam 1 Questions and Answers 100% Pass
- Exam (elaborations) • 11 pages • 2024
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GMS 6504 MODULE 1-3 Exam 1 
Questions and Answers 100% Pass 
What are System Independent Parameters? - Answer- Affinity 
Efficacy 
What are the parts of a system that are identified as System Dependent Parameters? - 
Answer- Number of receptors 
Cellular machinery 
Presence of other drugs 
- Competitive 
- Noncompetitive 
Affinity is - Answer- Thermokinetic propensity of drug to bind to receptor 
Based largely on ΔG 
Efficacy is - Answer- Magnitude of change of receptor shape/function upon drug...
![GMS 6504 Exam Questions and Answers 100% Correct!!](/docpics/5052512/6622c3ed5fd39_5052512_121_171.jpeg)
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GMS 6504 Exam Questions and Answers 100% Correct!!
- Exam (elaborations) • 13 pages • 2024
- Available in package deal
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Lipinski's rule of 5 - ANSWER-- Poor absorption or permeation are more likely when: 
1. mass greater than 500 Da 
2. highly lipophilic - logP > 5 
3. more than 5 hydrogen bond donors 
4. more than 10 hydrogen bond acceptors 
 
Partition coefficient - ANSWER-p = C(octanol)/C(water) 
- ratio of the equilibrium concentrations of dissolved substance in a two-phase system containing two largely immiscible solvents (water & octanol) 
- Log10(P) 
 
Improved Lipinski Parameters - ANSWER-1. Partition...
![GMS 6504 MODULE 1-3 Exam 1 Questions and Answers 100% Correct!!](/docpics/5052427/6622c0e191e05_5052427_121_171.jpeg)
-
GMS 6504 MODULE 1-3 Exam 1 Questions and Answers 100% Correct!!
- Exam (elaborations) • 7 pages • 2024
- Available in package deal
-
- $11.49
- + learn more
What are System Independent Parameters? - ANSWER-Affinity 
Efficacy 
 
What are the parts of a system that are identified as System Dependent Parameters? - ANSWER-Number of receptors 
Cellular machinery 
Presence of other drugs 
- Competitive 
- Noncompetitive 
 
Affinity is - ANSWER-Thermokinetic propensity of drug to bind to receptor 
 
Based largely on ΔG 
 
Efficacy is - ANSWER-Magnitude of change of receptor shape/function upon drug binding 
 
Based on atom/atom interactions 
 
What i...
![GMS 6504 MODULE 1-3 Exam 1 Questions and Answers 100% Pass](/docpics/4855617/660502c364686_4855617_121_171.jpeg)
-
GMS 6504 MODULE 1-3 Exam 1 Questions and Answers 100% Pass
- Exam (elaborations) • 11 pages • 2024
-
- $12.49
- + learn more
GMS 6504 MODULE 1-3 Exam 1 
Questions and Answers 100% Pass 
What are System Independent Parameters? - Answer- Affinity 
Efficacy 
What are the parts of a system that are identified as System Dependent Parameters? - 
Answer- Number of receptors 
Cellular machinery 
Presence of other drugs 
- Competitive 
- Noncompetitive 
Affinity is - Answer- Thermokinetic propensity of drug to bind to receptor 
Based largely on ΔG 
Efficacy is - Answer- Magnitude of change of receptor shape/function upon drug...
![GMS 6504 MODULE 1-3 Exam 1 Questions and Answers 100% Pass](/docpics/4765993/65f70ae4a87c0_4765993_121_171.jpeg)
-
GMS 6504 MODULE 1-3 Exam 1 Questions and Answers 100% Pass
- Exam (elaborations) • 11 pages • 2024
-
- $12.49
- + learn more
GMS 6504 MODULE 1-3 Exam 1 
Questions and Answers 100% Pass 
What are System Independent Parameters? - Answer- Affinity 
Efficacy 
What are the parts of a system that are identified as System Dependent Parameters? - 
Answer- Number of receptors 
Cellular machinery 
Presence of other drugs 
- Competitive 
- Noncompetitive 
Affinity is - Answer- Thermokinetic propensity of drug to bind to receptor 
Based largely on ΔG 
Efficacy is - Answer- Magnitude of change of receptor shape/function upon drug...
GMS 6504 MODULE 1-3 Exam 1 (2024) Questions With Complete
![GMS 6504 MODULE 1-3 Exam 1 Study Questions and Answers Already Passed 2024](/docpics/4677403/65e8292873eca_4677403_121_171.jpeg)
-
GMS 6504 MODULE 1-3 Exam 1 Study Questions and Answers Already Passed 2024
- Exam (elaborations) • 7 pages • 2024
-
- $10.99
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What are System Independent Parameters? - Affinity 
Efficacy 
 
What are the parts of a system that are identified as System Dependent Parameters? - Number of receptors 
Cellular machinery 
Presence of other drugs 
- Competitive 
- Noncompetitive 
 
Affinity is - Thermokinetic propensity of drug to bind to receptor 
 
Based largely on ΔG 
 
Efficacy is - Magnitude of change of receptor shape/function upon drug binding 
 
Based on atom/atom interactions 
 
What is the Occupancy Theory? - Re...
![GMS 6504 MODULE 1-3 Exam 1 Accurate 100%](/docpics/4656729/65e4e7a69fd6c_4656729_121_171.jpeg)
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GMS 6504 MODULE 1-3 Exam 1 Accurate 100%
- Exam (elaborations) • 7 pages • 2024
- Available in package deal
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- $10.49
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GMS 6504 MODULE 1-3 Exam 1 Accurate 100% 
 
What are System Independent Parameters? - ANSWER Affinity 
Efficacy 
 
What are the parts of a system that are identified as System Dependent Parameters? - ANSWER Number of receptors 
Cellular machinery 
Presence of other drugs 
- Competitive 
- Noncompetitive 
 
Affinity is - ANSWER Thermokinetic propensity of drug to bind to receptor 
 
Based largely on ΔG 
 
Efficacy is - ANSWER Magnitude of change of receptor shape/function upon drug binding ...
![GMS 6504 Exam Questions and Answers 100% Correct](/docpics/4601784/65dc402363139_4601784_121_171.jpeg)
-
GMS 6504 Exam Questions and Answers 100% Correct
- Exam (elaborations) • 13 pages • 2024
- Available in package deal
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- $11.99
- + learn more
GMS 6504 Exam Questions and Answers 100% CorrectGMS 6504 Exam Questions and Answers 100% CorrectGMS 6504 Exam Questions and Answers 100% CorrectGMS 6504 Exam Questions and Answers 100% CorrectLipinski's rule of 5 - ANSWER-- Poor absorption or permeation are more likely when: 
1. mass greater than 500 Da 
2. highly lipophilic - logP > 5 
3. more than 5 hydrogen bond donors 
4. more than 10 hydrogen bond acceptors 
 
Partition coefficient - ANSWER-p = C(octanol)/C(water) 
- ratio of the equili...
![GMS 6504 MODULE 1-3 Exam 1 Questions and Answers 100% Correct](/docpics/4601642/65dc3c27886fa_4601642_121_171.jpeg)
-
GMS 6504 MODULE 1-3 Exam 1 Questions and Answers 100% Correct
- Exam (elaborations) • 7 pages • 2024
- Available in package deal
-
- $10.99
- + learn more
GMS 6504 MODULE 1-3 Exam 1 Questions and Answers 100% CorrectGMS 6504 MODULE 1-3 Exam 1 Questions and Answers 100% CorrectGMS 6504 MODULE 1-3 Exam 1 Questions and Answers 100% CorrectGMS 6504 MODULE 1-3 Exam 1 Questions and Answers 100% Correct 
 
What are System Independent Parameters? - ANSWER-Affinity 
Efficacy 
 
What are the parts of a system that are identified as System Dependent Parameters? - ANSWER-Number of receptors 
Cellular machinery 
Presence of other drugs 
- Competitive 
- Non...
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