Ec50 Study guides, Class notes & Summaries

CP 10 EC50 and Emax Notice that Emax can never be directly observed. It is the asymptotic effect of the drug at infinite concentration. Even 10 times the C50 only reaches 90% of Emax. Kd definition Kd is the equilibrium binding constant. It is the concentration of unbound drug at which 50% of binding sites are occupied. What do we have to assume for C50 to be the same as Kd? That the effec

Describe the general structures of norepinephrine & epinephrine - Answer - aromatic ring with 2 hydroxyl groups - secondary hydroxyl group - amine group NE & EPI are susceptible to rapid metabolism/elimination by the enzymes ___ & ___ , resulting in extremely short half-lives - Answer COMT & MAO Predict the effects of N-alkyl group size on beta-AR activity - Answer inc bulkiness of N-alkyl group = inc binding affinity for beta-2 AR (more selective for beta-2 & binds longer) Which stru...

Pharmacokinetics - Answer-what the body does to the drug Pharmacodynamics - Answer-what the drug does to the body Pharmacogenetics - Answer-the study of how genetic variation affects an individual's response to drugs What is the role of lipid-soluble - Answer-lipid soluble drugs readily move across most biologic membranes due to solubility in the membrane lipid bilayers Potency - Answer-a measure of the amount of drug necessary to produce an effect the concentration of drug produ...

Katzung & Trevor's Pharmacology: Examination and Board Review INTRODUCTION 1. A 3-year-old is brought to the emergency department having just ingested a large overdose of tolbutamide, an oral antidiabetic drug. Tolbutamide is a weak acid with a pKa of 5.3. It is capable of entering most tissues, including the brain. On physical examination, the heart rate is 100/min, blood pressure 90/50 mm Hg, and respiratory rate 20/min. Which of the following statements about this case of tolb...

Pharmacodynamics (Exam 1) Verified Solutions (blank) agonist will produce a submaximal response... in the presence of a full agonist it will act as a (blank) ️partial, antagonist (blank) concerned with the study of biochemical and physiological effects of drugs and their mechanism of action.... more specifically it is concerned with the (blank) relationship ️pharmacodynamics, dose response (blank) is usually measured by the drug dose that produces 50% of maximal response usually k...

HESI Question bank pharm EXIT EXAM WITH QUESTIONS AND ANSWERS 2023 1. Which instructions should be included in the plan of care for a patient who is prescribed ferrous sulfate? a. Iron compounds are not taken orally b. Iron does not absorb c. Iron should only be taken at night d. Antacidsshould not be taken with iron 2. Which is the most common type of anemia? a. Iron deficiency b. Sickle cell anemia c. Folic acid deficiency d. B12 deficiency 3. Which antibiotic class disrupts ...

Receptor Macromolecule whose biological function changes when a drug binds to it What are the link between chemical actions and biological function? Receptors Emax maximum effect of a drug What happens when Emax is reached? Emax occurs when all receptors are bound What is in indication that spare receptors are present? When Emax is reached before all receptors are bound Agonist has affinity for a receptor as well as intrinsic activity at the receptor ...

PHARMACOLO MSN 571 Question Bank Pharm 2022- United State University 1. Which instructions should be included in the plan of care for a patient who is prescribed ferrous sulfate? a. Iron compounds are not taken orally b. Iron does not absorb c. Iron should only be taken at night d. Antacids should not be taken with iron 2. Which is the most common type of anemia? a. Iron deficiency b. Sickle cell anemia c. Folic acid deficiency d. B12 deficiency 3. Which antibiotic class disrupts fol...

Test Bank for Rau’s Respiratory Care Pharmacology, 9th Edition By Gardenhire, ISBN-10:0323299687 | Complete All Chapters. Which receptor site results in tachycardia, an increased potential for arrhythmias, and an increased cardiac output? a. Beta 1 receptor c. Alpha receptor b. Beta 2 receptor d. Delta receptor ANS: A Stimulation of the beta-1 receptors results in tachycardia, an increased potential for arrhythmias, and an increased cardiac output. In administering drugs to the pulmonary...

INVESTIGATED PHARMACY AND PHARMACOLOGY EXAM QUESTIONS AND ANSWERS What forms do eye medications come in? - CORRECT ANSWER -Suspensions, ointments, and serum drops What must be on a label for eye meds? - CORRECT ANSWER -Normal patient name, first and last name of client, and date BUT ALSO Name of medication, strength, which/both eyes, how many times per day, and for how long Going over with client is important for compliance! What are anaphylactic reactions? - CORRECT ANSWER -Sever...