P450 system - Study guides, Class notes & Summaries

NRNP 6566 MidtermStudy Guide NRNP 6566 Mid-term Study Guide Week 1 to 5 Week 1 1. Describe the cytochrome P450 system. Describe how inducers and inhibitors affect the cytochrome system and how that affects the half-life of medications. Cytochromes P450 (CYPs) are a superfamily of enzymes containing heme as a cofactor that function as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of various compounds, as well as ...

NR 546 Midterm Exam 2023/2024 Questions AND Answers Update A+ What should the PMHNP consider when prescribing chemical restraints? - Answer-- allergy status -prior med hx for adverse drug reactions r/t the meds ordered in the chemical restraint -state regulations regarding chemical restrains must be reviewed Are the PMHNP and other staff liable if the client has an allergic reaction or adverse side effects to the drugs used for chemical restraint? - Answer-No. The client has been court-...

NR546 Midterm Exam Test And 100% Correct Answers What should the PMHNP consider when prescribing chemical restraints? - ANSWER -allergy status -prior med hx for adverse drug reactions r/t the meds ordered in the chemical restraint -state regulations regarding chemical restrains must be reviewed Are the PMHNP and other staff liable if the client has an allergic reaction or adverse side effects to the drugs used for chemical restraint? - ANSWER No. The client has been court-ordered to...

Maryville NURS 615 Pharm Exam 2 Questions and Answers Already Passed Carbamazepine (Tegretol) can sometimes show subtherapeutic range due to what? Carbamazepine auto-induces metabolism, leading to lower levels despite good compliance What are the black box warnings for Carbamazepine? Dermatologic reactions 1. Steven's Johnson 2. Toxic epidermal necrolysis What lab test should be ordered for patients on Carbamazepine? CBC every 3-4 months because it can cause decreased WBC, decreased platelet...

NRNP 6566 Mid-term Study Guide Week 1 to 5 Week 1 1. Describe the cytochrome P450 system. Describe how inducers and inhibitors affect the cytochrome system and how that affects the half-life of medications. Cytochromes P450 (CYPs) are a superfamily of enzymes containing heme as a cofactor that function as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of various compounds, as well as for hormone synthesis and br...

Midterm Exam: NR565 / NR 565 (Latest Update 2024 / 2025) Advanced Pharmacology Fundamentals | Review Study Guide | 100% Correct | Grade A - Chamberlain Question: Beer's Criteria Answer: Includes five lists that describe certain medications and situations that include potentially inappropriate medication (PIM) use in older adults. PIM d/t medication-disease or medication-syndrome to be used cautiously in older adults Medications to be avoided or dosage, decreased in the presence ...

Exam 1: NURS 615/ NURS615 (Latest 2024/ 2025 Update) Advanced Pharmacotherapeutics Complete Guide |Qs & As| 100% Correct| Grade A (Verified Answers) Q: Explain first pass metabolism Answer: much of the drug is lost in the absorption process. The liver metabolizes many drugs, thus reduces the bio-availability of the drug. Q: What is the fasted route of absorption: Answer: The fastest route of absorption is inhalation, and not as mistakenly considered the IV administration. ...

During what trimester is a pregnant woman most at risk for adverse drug reactions with potential long term consequences? 1st trimester (fetus most at risk d/t rapid growth) What is BEERS criteria? Recommendations of medications inappropriate for elderly (65 and older), prescriber ultimately decides What is the CYP450 (cytochrome P450) liver enzyme system where medications are metabolized, can either be inducers or inhibitors and create drug-drug interactions CYP450 inducers Speed up metabo...

Midterm Exam: NR546/ NR 546 Psychopharmacology for the Psychiatric-Mental Health Nurse Practitioner MIDTERM Exam Review | Complete Guide Questions and Verified Answers| 2023/ 2024 Updated!! – Chamberlain What should the PMHNP consider when prescribing chemical restraints? - ANSWER -allergy status -prior med hx for adverse drug reactions r/t the meds ordered in the chemical restraint -state regulations regarding chemical restrains must be reviewed Are...

NR565 ADVANCED PHARMACOLOGY FUNDAMENTALS EXAM REVIEW QUESTIONS AND ANSWERS, GRADED A+ Pharmacokinetics - -The process by which drugs are absorbed, distributed within the body, metabolized, and excreted. Pharmacodynamics - -The study of what the drug does to the body Factors Affecting Drug Absorption - -Rate of dissolution Surface area Blood flow Lipid solubility pH partitioning Factors Affecting Drug Distribution - -Blood flow to tissues Ability to exit the vascular system Blood-bra...