Biomg - Study guides, Class notes & Summaries

What is the minimum number of nucleotides per amino acid required to specify all 20 amino acids? Correct Answer-3 nucleotide bases per amino acid Codon Correct Answer-a triplet of nucleotides that codes for a specific amino acid Translation occurs in such a way that these nucleotide triplets are read in a successive, nonoverlapping the key to the translation of genetic information, directing the synthesis of specific proteins Overlapping Correct Answer-AUACGAGUC -> is read like AU...

ligand Correct Answer-a small molecule that binds specifically to a larger one (i.e., protein). For example, a hormone is the ligand for its specific protein receptor [a molecule bound reversibly by a protein. binding site Correct Answer-the location (crevice or pocket) on a receptor protein to which a ligand binds induced fit Correct Answer-The change in shape of the active site of an enzyme so that it binds more snugly to the substrate, induced by entry of the substrate. Renders the subs...

What was originally considered to be the genetic material? Why? Correct Answer-Proteins were considered to be the genetic material because they were inherently more complex than DNA. Avery, McCarty, MacLeod experiment Correct Answer-First, think about Griffith's experiment and how even heat killed strains of S. pneumococcus still led to death of non pathogenic cells ⁃ Process: Grind up virulent cells, isolate the active genetic material ('transforming principle') and infuse it into non...

R1-R2C=NH Correct Answer-imine RO-CO-CH3 Correct Answer-acetyl R-SH Correct Answer-sulfhydryl/thiol R-CO-SR Correct Answer-thioester RO-PO2-OH Correct Answer-phosphoryl hydrogen bond Correct Answer-an electrostatic attraction between the O of one molecule and the H of another H must be bonded to F,O,N H bond acceptor Correct Answer-a LP on an electronegative atom H bond donor Correct Answer-an H bonded to F,O,N amphipathic molecule Correct

BIOMG 2800 Questions with Complete Solutions.

what does the biological activity of a protein depend on? Correct Answer-it's 3D structure and its interaction with other molecules prosthetic group Correct Answer-a metal ion or organic compound (other than an amino acid) covalently bound to a protein and essential to its activity modification types of amino acids Correct Answer- primary structure Correct Answer-a description of the covalent backbone of a polymer, including the sequence of monomeric subunits and any interchain and int...

What factors affect binding affinity? Correct Answer-Shape, charge, H-bonding, hydrophobics reversible binding Correct Answer-the association of a protein with its ligan is concentration-dependent K_d Correct Answer-the concentration of ligand at which 1/2 of the protein is ligand-bound K_d = k_d / k_a or k_off / k_on also = k_-1 / k_1 Calculate fraction of protein bound to ligand Correct Answer-[L] / ([L] + K_d) affinity and concentration association Correct Answer-if they bind at...

Henderson-Hasselbalch Equation Correct Answer-pH = pka + log([un]/[pro]) higher pka = higher affinity for H+ pH > pka, H+ is predominantly off pH < pka, H+ is predominantly on Ionizable Groups Correct Answer-Terminal Carboxyl Terminal Amino Acidic AA (ASP and GLU) Basic AA (HIS, CYS, LYS, TYR, and ARG) Aliphatic AA Correct Answer-Carbon based: "Guys! Alissa Values Likes on Instagram1" GLY, ALA, VAL LEU, ILE Aromatic AA Correct Answer-Form rings: "Pheobe is Tyred o...

BIOMG 3300 Unit 13 Objectives Questions with Correct Answers

Out of approximately 21,000 protein-coding genes in humans, how many are approoxiamtely devoted to cell signaling? Correct Answer-More than 7,000 What types of molecules can Signaling Molecules or Ligands be? (General Principle of Signaling) Correct Answer-Proteins, Peptides, Amino Acids, Nucleotides, Steroids, Fatty Acid Derivatives, Gases What must a cell have in order to accept a signal? (General Principle of Signaling) Correct Answer-A receptor What processes does the intracellular ...