Translocation - Study guides, Class notes & Summaries

Explore Essential Molecular Biology at UCL. Navigate the intricate realm of protein trafficking and translocation, unraveling the dynamics of protein movement from the ER. These notes, tailored for Year 1 students, provide a humanized academic guide, enhancing your comprehension of essential molecular processes. Please note that these materials are intended for personal use only and should be used in accordance with academic integrity guidelines.

MB (ASCP) 2022 - Translocations, Diseases, Pharma, Polymerases, & more Chronic Myeloid Leukemia (CML) t(9;22) BCR-ABL translocation Ewing sarcoma t(11;22) EWS-FLI1 Acute Lymphocytic Leukemia (ALL) t(9;22) BCR-ABL p190 protein Follicular Lymphoma t(14;18) BCL2 translocation Mantle Cell Lymphoma t(11;14) bcl-1 translocation CCND1-IgH Burkitt Lymphoma t(8;14) MYC gene translocation Rhabdomyosarcoma (alveolar); Cancer/solid tumor t(2;13) or t(1;13) PAX3-FKHR and PAX7-FKHR "ARMS" translocatio...

How are chromosomes labeled? Correct Answer-chromosome -> arms -> regions -> bands -> subbands banding pattern depends on type of stain used del = deletion dup = duplication inv = inversion t = translocation ter = terminal (pter/qter) 1- What are the two arms of a Chromosome? 2- What are the three positions of the centromere? Correct Answer-P- Short Q- Long arm 2- metacentric = centromere located centrally *Acrocentric* = centromere located terminally with satellit...

What are the purines and pyrimidines? - Answer-purines: adenine, guanine pyrimidines: cytosine, uracil, thymine What are some examples of the cause of mutations in DNA? - Answer-cellular metabolism, UV light exposure, ionizing radiation, chemical exposure, replication errors What happens when the DNA is damaged/a mutation occurs? - Answer-cell cycle checkpoint activation, transcriptional program activation, DNA repair, apoptosis What is the definition of a gene? - Answer-A segment of D...

E. coli RNA Polymerase II - Answer DNA template, product: mRNA RNA Polymerase I - Answer DNA template Location: Nucleous Products: 18s, 5.8s, 28s rRNA RNA Polymerase II - Answer DNA template Location: Nucleus Products: mRNA, snRNA RNA Polymerase III - Answer DNA template Location: Nucleus Product: tRNA, 5s rRNA, snRNA Mitochondrial RNA Polymerase - Answer DNA template, product: mRNA Mammalian DNA polymerase α - Answer DNA template, product: primers HCV RNA Polymerase - A...

Rights of Way Pesticides Practice Exam Questions and Answers Growth regulator herbicides -Answer-disrupt the hormone balance and protein synthesis in plants, causing growth abnormalities. Growth regulators selectively kill broadleaf weeds in grass stands. Grasses generally are tolerant to these chemicals, but injury can occur if herbicides are applied at the wrong growth stage or at high rates. These herbicides translocate to the growing points of the plants, and injury symptoms appear in...

Chapter: Midterm Multiple Choice 1. Which of the following cellular exchange mechanisms requires adenosine triphosphate (ATP) and the use of a carrier protein? A) Facilitated diffusion B) Osmosis C) Active transport D) Simple diffusion Ans: C Complexity: Easy Ahead: Basic Cell Function and Structure Subject: Chapter 1 Title: Cellular Function 2. What is a key determinant of osmotic pressure? A) Water B) Sodium C) Albumin D) Glucose Ans: B Complexity: Easy Ahead: Basic Cell Fu...

ABGC Practice Questions and Answers 2024 Updated Under what circumstances should an infant with clinical features of Down syndrome be karyotyped? A. Only if the parents desire more children B. Only if the mother is younger than 35 years old C. Only if not all of the features of Down syndrome are present D. Only if the mother has had 3 early miscarriages E. Always - CORRECT ANSWER-E. Always What is the parental origin and stage of meiosis when most meiotic errors occur resulting...

Exam 3: NURS611/ NURS 611 (Latest 2023/ 2024) Advanced Pathophysiology Exam | 100% Correct | 200+ Practice Questions and Verified Answers with Rationales | Grade A- Maryville QUESTION What change is observed in leukocytes during an allergic disorder (type I hypersensitivity) often caused by asthma, hay fever, and drug reactions? a. Neutrophilia c. Eosinophilia b. Basophilia d. Monocytosis Answer: C Eosinophilia is an absolute increase (more than 450/µL) in the total number...

What is the most common electron carrier in biological systems? Correct Answer-NAD During the process of group translocation, glucose is brought into the cell and is chemically modified into what compound, which prevents it from leaving the cell? Correct Answer-Glucose-6-phosphate Where does the Krebs cycle take place in bacteria? Correct Answer-Cytoplasm For the most part, what type of energy operates cell transactions? Correct Answer-Chemical Which of the following is the substrate...