Xeroderma pigmentosum - Study guides, Class notes & Summaries

The LEP gene codes for an anorexigenic hormone. Interestingly, breastfeeding has been shown to alter methylation of the promoter of this gene, leading to increased LEP expression. What is likely happening in response to breastfeeding? Correct Answer- Breastfeeding decreases the methylation of the promoter of the LEP gene, increasing the spacing between nucleosomes. A patient with xeroderma pigmentosum is prone to developing multiple skin cancers starting in childhood. This occurs because o...

BIO 188 XERODERMA PIGMENTOSUM CASE STUDY REVIEW ( REAL PATIENT)BIO 188 XERODERMA PIGMENTOSUM CASE STUDY REVIEW ( REAL PATIENT)BIO 188 XERODERMA PIGMENTOSUM CASE STUDY REVIEW ( REAL PATIENT)

MCT NBME Review Questions and Answers B - Ans:-(Marks' Medical Biochemistry Chapter 5) A patient was diagnosed with one of the types of sphingolipidoses, which are congenital diseases involving the ability to degrade sphingolipids. All sphingolipids have in common which one of the following? A. a glycerol backbone B. ceramide C. phosphorylcholine D. N-acetylneuraminic acid (NANA) B - Ans:-(Marks' Medical Biochemistry Chapter 6) Protein kinases phosphorylate proteins only at certa...

Fundamental Molecular Biology Exam Questions and Answers Define mutation - Answer-mutations are changes in the genetic material of a cell (or virus) Define gene - Answer-A gene is a genomic sequence (DNA or RNA) directly encoding functional product molecules, either RNA or protein What is a spontaneous mutation? - Answer-a naturally occurring mutation in the absence of a mutagen How often to spontaneous mutations occur? - Answer-3 new mutations per 10^8 base pairs per generation. 200 ne...

Chagas Disease - ***Caused by Trypanosoma cruzi parasite passed in the feces of Reduviidae/kissing bug Penetrates broken skin or intact mucous membranes forming a pseudocyst releasing inflammatory infiltrates into myocytes; stains with Giemsa & Wright Romana sign occurs when portal of entry is the conjunctiva or eyelid May resulting in: Enlarged heart- CHF, sudden cardiac arrest Enlarged esophagus- difficulty swallowing Enlarged colon- abdominal pain or constipation Treat with benznida...

Chagas Disease - Caused by Trypanosoma cruzi parasite passed in the feces of Reduviidae/kissing bug Penetrates broken skin or intact mucous membranes forming a pseudocyst releasing inflammatory infiltrates into myocytes; stains with Giemsa & Wright Romana sign occurs when portal of entry is the conjunctiva or eyelid May resulting in: Enlarged heart- CHF, sudden cardiac arrest Enlarged esophagus- difficulty swallowing Enlarged colon- abdominal pain or constipation Treat with benzn...

MMSC490 Exam 2 Questions with Complete Answers Which eukaryotic DNA polymerase replicates the lagging strand in the 3ʹ to 5ʹ direction? a. α b. γ c. δ d. None of the above; the lagging strand is replicated in the 5ʹ to 3ʹ direction. - Answer ️️ -d. None of the above; the lagging strand is replicated in the 5ʹ to 3ʹ direction. DNA polymerases can synthesize DNA: a. de novo, by catalyzing the polymerization of free dNTPs. b. by adding dNTPs to complementary dNTPs on a single-...

BIOCHEM C785 Readiness Exam[ ALL ANSERS 100% CORRECT] The LEP gene codes for an anorexigenic hormone. Interestingly, breastfeeding has been shown to alter methylation of the promoter of this gene, leading to increased LEP expression. What is likely happening in response to breastfeeding? Correct answer- Breastfeeding decreases the methylation of the promoter of the LEP gene, increasing the spacing between nucleosomes. A patient with xeroderma pigmentosum is prone to developing multiple sk...

BioChem C785 Biochemistry preassessment with complete solution Assuming 100% reaction efficiency, how many DNA copies are created after the completion of four complete PCR cycles? - Answer ️️ -16 What is the function of DNA polymerase in the process of PCR? - Answer ️️ -It recognizes the primers and uses the available dNTPs to replicate the template DNA sequence. What are possible blood types of the parents of a patient with blood type AB? - Answer ️️ -A and B − Amino Acid...