Ketogenesis - Study guides, Class notes & Summaries

What is the role of adipose in metabolism? Storage of triacylglycerols as a source of energy that can be released as FFAs under fasted state conditions; other roles include body weight homeostasis, coagulation, immunity, vascular tone control, appetite regulation, glucose/lipid metabolism, reproduction, angiogenesis what are the direct products of B-oxidation? NADH + FADH2 (used in ETC to produce ATP), Acetyl CoA (substrate for ketogenesis, allosteric activator of pyruvate carboxylase) An ...

NURS 5315 Advanced PathophysiologyOvarian cancer site of metastasis? - correct answer Peritoneal surfaces, omentum (fold of peritoneum connecting the stomach with other abdominal organs), *liver* The increased NADH/NAD+ ratio in the liver from ethanol causes: - correct answer 1. Pyruvate --> lactic acid, causing lactic acidosis 2. Oxaloacetate --> malate. This prevents gluconeogenesis and leads to hypoglycemia 3. Glyceraldehyde-3-phosphate --> glycerol 3- phosphate and combines wit...

NURS 5315 Advanced Pathophysiology Ovarian cancer site of metastasis? Peritoneal surfaces, omentum (fold of peritoneum connecting the stomach with other abdominal organs), liver The increased NADH/NAD+ ratio in the liver from ethanol causes: 1. Pyruvate --> lactic acid, causing lactic acidosis 2. Oxaloacetate --> malate. This prevents gluconeogenesis and leads to hypoglycemia 3. Glyceraldehyde-3-phosphate --> glycerol 3- phosphate and combines with fatty acids to form triglyce...

Ovarian cancer site of metastasis? - Answer-Peritoneal surfaces, omentum (fold of peritoneum connecting the stomach with other abdominal organs), *liver* The increased NADH/NAD+ ratio in the liver from ethanol causes: - Answer-1. Pyruvate --> lactic acid, causing lactic acidosis 2. Oxaloacetate --> malate. This prevents gluconeogenesis and leads to hypoglycemia 3. Glyceraldehyde-3-phosphate --> glycerol 3- phosphate and combines with fatty acids to form triglycerides in the liver,...

Final Exam - UNE Medical Biochemistry 1005 Questions With 100% Correct Answers What are the direct products of B-Oxidation? - answer1) NADH, FADH2 used in ETC --> ATP 2) Acetyl-CoA i) substrate for ketogenesis ii) Allosterically activates pyruvate carboxylase --> gluconeogenesis 3) ATP used in anabolic process in fasted state i) Gluconeogenesis ii) Urea Cycle An 11-year-old girl is brought to the emergency department by her father. He reports she has recently been very thirsty an...

An individual goes to bed around 8 pm and doesn't wake up until 9 am the next morning. During this time, which of the following is the primary oxidizable substrate in the skeletal muscle? - ANSWERSFree fatty acids Under fasted conditions as described above, the skeletal muscle and liver would be oxidizing free fatty acids as a means of producing ATP. A well, 2-year-old girl presents to the clinic with symptoms of a viral illness. Her parents report she has had bouts of vomiting and diarrh...

Under fasting conditions (ratio of insulin to glucagon <1), elevated glucagon will activate which of the following enzymes? - Hormone sensitive lipase The process of ketogenesis refers to the conversion of acetyl CoA to which of the following compounds? - D-3-hydroxybutyrate or B-hydroxybutyrate During the fasted state, lipolysis is facilitated by the action of hormone sensitive lipase. This enzyme requires which of the following post - translational modification for activation? -...

In the fasted state, fatty acyl-CoAs are transported across the mitochondrial membrane. The transport of fatty acids via carnitine palmitoyl transferase I (CPT-1) can be directly inhibited by which of the following compounds? a. Malonyl-CoA b. Carnitine c. Palmitate d. Acetyl-CoA - ANSWERSMalonyl-CoA In the fasted state, fatty acyl-CoAs are transported across the mitochondrial membrane. The transport of fatty acids via carnitine palmitoyl transferase I (CPT-1) can be directly inhi...

short chain fatty acids and medium chain fatty acids enter mitochondria by: - Diffusion Under fasting conditions (ratio of insulin to glucagon <1), elevated glucagon will activate which of the following enzymes? - Hormone sensitive lipase the process of ketogenesis refers to the conversion of acetyl-CoA to which of the following compounds? - B-hydroxybutyrate

UNE Medical Biochemistry Unit 3 Review (For this guide, I made the questions from the video lectures, study guides, and quiz/test reviews) Rated A+ What occurs when glucagon is high and insulin is low? Beta-oxidation During the fasted state, the liver uses ______ as fuel and the pathway is _______. Fatty acids, Lipolysis in the adipose During the fasted state, the red blood cell uses ______ as fuel and the pathway is _______. Glucose, Hepatic glycogenolysis, and gluconeogenesis During t...